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Case of catastrophic antiphospholipid syndrome presenting as neuroretinitis and vaso-occlusive retinopathy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yun, Young In | - |
dc.contributor.author | Kim, Ji Hyun | - |
dc.contributor.author | Lim, Seon Hee | - |
dc.contributor.author | Ahn, Yo Han | - |
dc.contributor.author | Kang, Hee Gyung | - |
dc.contributor.author | Ha, Il-Soo | - |
dc.contributor.author | Oh, Baek-Lok | - |
dc.date.accessioned | 2021-02-25T05:23:36Z | - |
dc.date.available | 2021-02-25T14:26:02Z | - |
dc.date.issued | 2020-12-09 | - |
dc.identifier.citation | BMC Ophthalmology. 2020 Dec 09;20(1):482 | ko_KR |
dc.identifier.issn | 1471-2415 | - |
dc.identifier.uri | https://hdl.handle.net/10371/173406 | - |
dc.description.abstract | Background
Ocular involvement in catastrophic antiphospholipid syndrome (CAPS), a rare, life-threatening form of antiphospholipid syndrome (APS) that results in multiorgan failure and a high mortality rate, has rarely been reported. Case presentation A 15-year-old girl presented with sudden vision blurring in both eyes. She had marked optic disc swelling and macular exudates in the right eye and intra-arterial white plaques, a few retinal blot hemorrhages, and a white ischemic retina in the left eye. Systemic examination revealed she had acute kidney injury with thrombotic microangiopathy (TMA), multiple cerebral infarcts, valvular dysfunction, and a high titer of triple aPL. Thus, she was diagnosed with CAPS involving the brain, eyes, heart, and kidneys. Plasma exchange and the administration of glucocorticoids, immunoglobulin, warfarin, and rituximab brought a sustained recovery of the TMA, visual symptoms, and echocardiographic findings. Conclusions Ocular involvement of both vaso-occlusive retinopathy, an APS-related thrombotic microangiopathy, and neuroretinitis, a non-thrombotic microangiopathy, can occur as an initial presentation of CAPS. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BMC | ko_KR |
dc.subject | Catastrophic antiphospholipid syndrome | - |
dc.subject | Antiphospholipid syndrome | - |
dc.subject | Neuroretinitis | - |
dc.subject | Vaso-occlusive retinopathy | - |
dc.subject | Thrombotic microangiopathy | - |
dc.title | Case of catastrophic antiphospholipid syndrome presenting as neuroretinitis and vaso-occlusive retinopathy | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 윤영인 | - |
dc.contributor.AlternativeAuthor | 김지현 | - |
dc.contributor.AlternativeAuthor | 임선희 | - |
dc.contributor.AlternativeAuthor | 안요한 | - |
dc.contributor.AlternativeAuthor | 강희경 | - |
dc.contributor.AlternativeAuthor | 하일수 | - |
dc.contributor.AlternativeAuthor | 오백록 | - |
dc.identifier.doi | 10.1186/s12886-020-01755-9 | - |
dc.citation.journaltitle | BMC Ophthalmology | ko_KR |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2021-01-27T09:58:53Z | - |
dc.citation.number | 1 | ko_KR |
dc.citation.startpage | 482 | ko_KR |
dc.citation.volume | 20 | ko_KR |
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