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Bidirectional association between asthma and otitis media in children

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Authors
Kim, So Young; Kim, Hye-Rim; Min, Chanyang; Choi, Hyo Geun
Issue Date
2021-01-09
Publisher
BMC
Citation
Allergy, Asthma & Clinical Immunology. 2021 Jan 09;17(1):7
Keywords
AsthmaOtitis mediaCohort studiesEpidemiology
Abstract
Background
This study explored the reciprocal association between otitis media and asthma in children.

Methods
The 2002–2013 Korean Health Insurance Review and Assessment Service-National Sample Cohort participants < 15 years old were used. In study I, 14,665 asthma patients from 2002 through 2005 were selected. The asthma patients were matched 1:1 with the control I group, and the occurrence of otitis media was followed until 2013. In study II, 27,043 otitis media patients from 2002 through 2005 were selected. The otitis media patients were matched 1:1 with the control II group, and the occurrence of asthma was followed until 2013. Stratified Cox proportional hazard models were used to analyze the hazard ratio (HRs) of asthma for otitis media (study I) and otitis media for asthma (study II).

Results
The HR for otitis media was 1.46 in asthma patients (95% confidence interval [CI] = 1.40–1.52, P < 0.001). The HR for asthma was 1.43 in otitis media patients (95% confidence interval [CI] = 1.36–1.50, P < 0.001).

Conclusion
Asthma and otitis media have a bidirectional association in children.
ISSN
1710-1492
Language
English
URI
https://hdl.handle.net/10371/173587
DOI
https://doi.org/10.1186/s13223-020-00500-7
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Graduate School of Public Health (보건대학원)Dept. of Public Health (보건학과)Journal Papers (저널논문_보건학과)
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