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Lung transplantation for severe COVID-19-related ARDS
DC Field | Value | Language |
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dc.contributor.author | Ko, Ryoung-Eun | - |
dc.contributor.author | Oh, Dong Kyu | - |
dc.contributor.author | Choi, Sun Mi | - |
dc.contributor.author | Park, Sunghoon | - |
dc.contributor.author | Park, Ji Eun | - |
dc.contributor.author | Lee, Jin Gu | - |
dc.contributor.author | Kim, Young Tae | - |
dc.contributor.author | Jeon, Kyeongman | - |
dc.date.accessioned | 2022-04-12T04:34:37Z | - |
dc.date.available | 2022-04-12T04:34:37Z | - |
dc.date.created | 2022-03-31 | - |
dc.date.issued | 2022-02 | - |
dc.identifier.citation | Therapeutic Advances in Respiratory Disease, Vol.16, p. 175346662210810 | - |
dc.identifier.issn | 1753-4658 | - |
dc.identifier.uri | https://hdl.handle.net/10371/177992 | - |
dc.description.abstract | Background: Lung transplantation (LT) is the gold standard for various end-stage chronic lung diseases and could be a salvage therapeutic option in acute respiratory distress syndrome (ARDS). However, LT is uncertain in patients with coronavirus disease 2019 (COVID-19)-related ARDS who failed to recover despite optimal management including extracorporeal membrane oxygenation (ECMO). This study aims to describe the pooled experience of LT for patients with severe COVID-19-related ARDS in Korea. Methods: A nationwide multicenter retrospective observational study was performed with consecutive LT for severe COVID-19-related ARDS in South Korea (June 2020-June 2021). Data were collected and compared with other LTs after bridging with ECMO from the Korean Organ Transplantation Registry. Results: Eleven patients with COVID-19-related ARDS underwent LT. The median age was 60.0 years [interquartile range (IQR), 57.5-62.5; six males]. All patients were supported with venovenous ECMO at LT listing and received rehabilitation before LT. Patients were transplanted at a median of 49 (IQR, 32-66) days after ECMO cannulation. Primary graft dysfunction within 72 h of LT developed in two (18.2%). One patient expired 4 days after LT due to sepsis and one patient underwent retransplantation for graft failure. After a median follow-up of 322 (IQR, 299-397) days, 10 patients are alive and recovering well. Compared with other LTs after bridging with ECMO (n = 27), post-transplant outcomes were similar between the two groups. Conclusions: LT in patients with unresolving COVID-19-related ARDS were effective with reasonable short-term outcome. | - |
dc.language | 영어 | - |
dc.publisher | SAGE Publications | - |
dc.title | Lung transplantation for severe COVID-19-related ARDS | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/17534666221081035 | - |
dc.citation.journaltitle | Therapeutic Advances in Respiratory Disease | - |
dc.identifier.wosid | 000767189500001 | - |
dc.identifier.scopusid | 2-s2.0-85125833679 | - |
dc.citation.startpage | 175346662210810 | - |
dc.citation.volume | 16 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Young Tae | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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