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Risk Factor and Treatment of Vaginal Intraepithelial Neoplasia After Hysterectomy for Cervical Intraepithelial Neoplasia
DC Field | Value | Language |
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dc.contributor.author | Kim, Ju-Hyun | - |
dc.contributor.author | Kim, Jooyoung | - |
dc.contributor.author | Kim, Kidong | - |
dc.contributor.author | No, Jae Hong | - |
dc.contributor.author | Kim, Yong Beom | - |
dc.contributor.author | Suh, Dong Hoon | - |
dc.date.accessioned | 2022-06-22T08:34:28Z | - |
dc.date.available | 2022-06-22T08:34:28Z | - |
dc.date.created | 2022-05-20 | - |
dc.date.issued | 2022-04 | - |
dc.identifier.citation | Journal of lower genital tract disease, Vol.26 No.2, pp.147-151 | - |
dc.identifier.issn | 1526-0976 | - |
dc.identifier.uri | https://hdl.handle.net/10371/183058 | - |
dc.description.abstract | Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the ASCCP.OBJECTIVES: The aim of the study were to identify the risk factors for recurrent vaginal intraepithelial neoplasia (VaIN)1+ and to evaluate the efficacy of laser vaporization in patients who underwent hysterectomy for the treatment of cervical intraepithelial neoplasia (CIN). METHODS: Medical records of 374 women who underwent hysterectomy for the treatment of CIN were retrospectively reviewed. Recurrence was defined as VaIN1+ diagnosis by colposcopy-directed biopsy. RESULTS: Among 374 patients, 36 (9.6%) had VaIN1+ during a median follow-up of 32 (0-193) months: 13 (3.5%) had VaIN1, 6 (1.6%) VaIN2, 15 (4.0%) VaIN3, and 2 (0.5%) invasive cancer. Multivariate analysis showed that age of greater than 50 years was the only independent risk factor for VaIN1+ recurrence (odds ratio, 3.359; 95% CI, 1.60-7.07; p = .001). Among the 34 patients with VaIN, 21 (61.8%) were treated with laser vaporization and 11 (32.3%) were observed without treatment. Time to second recurrence was longer in the VaIN treated by laser vaporization group than that in the observation group (mean time to subsequent recurrence, 128.7 [95% CI, 101.4-156.0] vs. 41.8 [15.7-67.9] months; p = .003). Moreover, laser vaporization (hazard ratio, 0.125; 95% CI, 0.03-0.59; p = .009) was the only independent good prognostic factor for the second VaIN1+ recurrence. CONCLUSIONS: Patients older than 50 years who underwent hysterectomy for the treatment of CIN might be highly at risk of VaIN1+. Laser vaporization is the only independent prognostic factor that might prevent the second VaIN1+ recurrence. | - |
dc.language | 영어 | - |
dc.publisher | NLM (Medline) | - |
dc.title | Risk Factor and Treatment of Vaginal Intraepithelial Neoplasia After Hysterectomy for Cervical Intraepithelial Neoplasia | - |
dc.type | Article | - |
dc.identifier.doi | 10.1097/LGT.0000000000000664 | - |
dc.citation.journaltitle | Journal of lower genital tract disease | - |
dc.identifier.scopusid | 2-s2.0-85128000004 | - |
dc.citation.endpage | 151 | - |
dc.citation.number | 2 | - |
dc.citation.startpage | 147 | - |
dc.citation.volume | 26 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Yong Beom | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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