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Comparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia

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dc.contributor.authorLi, Ling-
dc.contributor.authorRami, Fatima Zahra-
dc.contributor.authorPiao, Yan Hong-
dc.contributor.authorLee, Bo Mi-
dc.contributor.authorKim, Woo-Sung-
dc.contributor.authorSui, Jing-
dc.contributor.authorKim, Sung-Wan-
dc.contributor.authorLee, Bong Ju-
dc.contributor.authorKim, Jung Jin-
dc.contributor.authorYu, Je-Chun-
dc.contributor.authorLee, Kyu Young-
dc.contributor.authorWon, Seung-Hee-
dc.contributor.authorLee, Seung-Hwan-
dc.contributor.authorKim, Seung-Hyun-
dc.contributor.authorKang, Shi Hyun-
dc.contributor.authorKim, Euitae-
dc.contributor.authorChung, Young Chul-
dc.date.accessioned2022-06-24T00:32:26Z-
dc.date.available2022-06-24T00:32:26Z-
dc.date.created2022-05-12-
dc.date.issued2022-01-
dc.identifier.citationEarly Intervention in Psychiatry-
dc.identifier.issn1751-7885-
dc.identifier.urihttps://hdl.handle.net/10371/183923-
dc.description.abstract© 2022 John Wiley & Sons Australia, Ltd.Aim: Research on psychotic disorder not otherwise specified (PNOS) that clearly mentions its subgroups is very rare. This study was conducted to identify the demographic and clinical features, cognitive function, and 1-year outcomes of patients with early stage PNOS compared with those with early stage schizophrenia (SZ). Methods: The study subjects were 54 and 321 patients with PNOS and SZ, respectively, who were registered at least more than 1 year ago. Due to drop out, only 37 and 210 patients with PNOS and SZ were evaluated at the 1-year follow-up. We compared clinical variables (duration of untreated psychosis, symptom severity, self-rating scales, and so on), cognitive function, and short-term outcomes (treatment response, remission, compliance, drop out, relapse) between the two groups. Results: The patients with PNOS were associated with higher diagnostic stability (53.7%) compared with those in previous studies. They had lower symptom severity, better treatment response at 2 months and higher remission rates at 12 months, but poorer compliance at 6 months compared with patients with SZ. Level of cognitive impairment in PNOS was intermediate between those of SZ patients and healthy controls. Conclusions: These findings indicate that PNOS has unique clinical features, suggesting that it should be treated as a distinct clinical syndrome. At the same time, however, prevention of its possible progression to other psychotic disorders in some patients with PNOS is also important.-
dc.language영어-
dc.publisherBlackwell Publishing Inc.-
dc.titleComparison of clinical features and 1-year outcomes between patients with psychotic disorder not otherwise specified and those with schizophrenia-
dc.typeArticle-
dc.citation.journaltitleEarly Intervention in Psychiatry-
dc.identifier.wosid000751756700001-
dc.identifier.scopusid2-s2.0-85124465763-
dc.identifier.rimsid160926-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorKim, Euitae-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
Appears in Collections:
College of Natural Sciences (자연과학대학)Brain and Cognitive Sciences (뇌인지과학과)Journal Papers (저널논문_뇌인지과학과)
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