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Validation for measurements of skeletal muscle areas using low-dose chest computed tomography
DC Field | Value | Language |
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dc.contributor.author | Lim, Woo Hyeon | - |
dc.contributor.author | Park, Chang Min | - |
dc.date.accessioned | 2022-06-24T08:26:03Z | - |
dc.date.available | 2022-06-24T08:26:03Z | - |
dc.date.created | 2022-02-08 | - |
dc.date.created | 2022-02-08 | - |
dc.date.created | 2022-02-08 | - |
dc.date.created | 2022-02-08 | - |
dc.date.created | 2022-02-08 | - |
dc.date.issued | 2022-12 | - |
dc.identifier.citation | Scientific Reports, Vol.12 No.1, p. 463 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://hdl.handle.net/10371/184040 | - |
dc.description.abstract | Various methods were suggested to measure skeletal muscle areas (SMAs) using chest low-dose computed tomography (chest LDCT) as a substitute for SMA at 3rd lumbar vertebra level (L3-SMA). In this study, four SMAs (L1-SMA, T12-erector spinae muscle areas, chest wall muscle area at carina level, pectoralis muscle area at aortic arch level) were segmented semi-automatically in 780 individuals taking concurrent chest and abdomen LDCT for healthcare screening. Four SMAs were compared to L3-SMA and annual changes were calculated from individuals with multiple examinations (n = 101). Skeletal muscle index (SMI; SMA/height(2)) cut-off for sarcopenia was determined by lower 5th percentile of young individuals (age <= 40 years). L1-SMA showed the greatest correlation to L3-SMA (men, R-2 = 0.7920; women, R-2 = 0.7396), and the smallest annual changes (0.3300 +/- 4.7365%) among four SMAs. L1-SMI cut-offs for determining sarcopenia were 39.2cm(2)/m(2) in men, and 27.5cm(2)/m(2) in women. Forty-six men (9.5%) and ten women (3.4%) were found to have sarcopenia using L1-SMI cut-offs. In conclusion, L1-SMA could be a reasonable substitute for L3-SMA in chest LDCT. Suggested L1-SMI cut-offs for sarcopenia were 39.2cm(2)/m(2) for men and 27.5cm(2)/m(2) for women in Asian. | - |
dc.language | 영어 | - |
dc.publisher | Nature Publishing Group | - |
dc.title | Validation for measurements of skeletal muscle areas using low-dose chest computed tomography | - |
dc.type | Article | - |
dc.identifier.doi | 10.1038/s41598-021-04492-1 | - |
dc.citation.journaltitle | Scientific Reports | - |
dc.identifier.wosid | 000741645800131 | - |
dc.identifier.scopusid | 2-s2.0-85122689374 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 463 | - |
dc.citation.volume | 12 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Park, Chang Min | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | OBSTRUCTIVE PULMONARY-DISEASE | - |
dc.subject.keywordPlus | LUNG-CANCER MORTALITY | - |
dc.subject.keywordPlus | SARCOPENIA | - |
dc.subject.keywordPlus | DYSFUNCTION | - |
dc.subject.keywordPlus | SYSTEM | - |
dc.subject.keywordPlus | INDEX | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | MASS | - |
dc.subject.keywordPlus | L3 | - |
dc.subject.keywordPlus | CT | - |
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