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Preoperative Serum Alkaline Phosphatase and Neurological Outcome of Cerebrovascular Surgery
DC Field | Value | Language |
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dc.contributor.author | Park, Seongjoo | - |
dc.contributor.author | Choi, Eun-Su | - |
dc.contributor.author | Jung, Hee-Won | - |
dc.contributor.author | Lee, Ji-Youn | - |
dc.contributor.author | Park, Jin-Woo | - |
dc.contributor.author | Bang, Jae-Seung | - |
dc.contributor.author | Jeon, Yeong-Tae | - |
dc.date.accessioned | 2022-08-25T01:14:21Z | - |
dc.date.available | 2022-08-25T01:14:21Z | - |
dc.date.created | 2022-06-27 | - |
dc.date.issued | 2022-06 | - |
dc.identifier.citation | Journal of Clinical Medicine, Vol.11 No.11, p. 2981 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://hdl.handle.net/10371/184396 | - |
dc.description.abstract | This study evaluated the relationship between the preoperative alkaline phosphatase (ALP) level and major postoperative neurological complications in patients undergoing cerebral bypass surgery. This was a retrospective analysis of a prospective database of all patients undergoing cerebral bypass surgery after a diagnosis of cerebrovascular stenosis or occlusion between May 2003 and August 2017. The patients were divided into tertiles based on serum alkaline phosphatase (ALP) levels (low: <63, intermediate: 63 similar to 79, and high: ALP > 79 IU/mL). The incidence of neurological events according to ALP level was analyzed. The study analyzed 211 cases. The incidence of acute infarction was highest in the third serum ALP tertile (5.7% vs. 2.9% vs. 16.9% in the first, second, and third tertile, respectively, p = 0.007). Logistic regression analysis showed that the third tertile of serum ALP was an independent predictor of acute cerebral infarction (odds ratio 3.346, 95% confidence interval 1.026-10.984, p = 0.045). On Kaplan-Meier time-to-event curves, the incidence of acute infarction increased significantly with ALP (log rank = 0.048). Preoperative serum ALP level can be used as a biomarker to predict acute cerebral infarction in patients undergoing cerebral bypass surgery for vascular stenosis or occlusion. | - |
dc.language | 영어 | - |
dc.publisher | MDPI AG | - |
dc.title | Preoperative Serum Alkaline Phosphatase and Neurological Outcome of Cerebrovascular Surgery | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/jcm11112981 | - |
dc.citation.journaltitle | Journal of Clinical Medicine | - |
dc.identifier.wosid | 000809870700001 | - |
dc.citation.number | 11 | - |
dc.citation.startpage | 2981 | - |
dc.citation.volume | 11 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Jeon, Yeong-Tae | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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