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Pretransplant and Posttransplant Alcohol Consumption and Outcomes in Kidney Transplantation: A Prospective Multicenter Cohort Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jung, Hee-Yeon | - |
dc.contributor.author | Jeon, Yena | - |
dc.contributor.author | Huh, Kyu Ha | - |
dc.contributor.author | Park, Jae Berm | - |
dc.contributor.author | Kim, Myung-Gyu | - |
dc.contributor.author | Lee, Sik | - |
dc.contributor.author | Han, Seungyeup | - |
dc.contributor.author | Ro, Han | - |
dc.contributor.author | Yang, Jaeseok | - |
dc.contributor.author | Ahn, Curie | - |
dc.contributor.author | Cho, Jang-Hee | - |
dc.contributor.author | Park, Sun-Hee | - |
dc.contributor.author | Kim, Yong-Lim | - |
dc.contributor.author | Kim, Chan-Duck | - |
dc.date.accessioned | 2022-09-29T03:17:25Z | - |
dc.date.available | 2022-09-29T03:17:25Z | - |
dc.date.created | 2022-07-21 | - |
dc.date.issued | 2022-05 | - |
dc.identifier.citation | Transplant International, Vol.35, p. 10243 | - |
dc.identifier.issn | 0934-0874 | - |
dc.identifier.uri | https://hdl.handle.net/10371/184566 | - |
dc.description.abstract | The impact of pretransplant and posttransplant alcohol consumption on outcomes in kidney transplant recipients (KTRs) is uncertain. Self-reported alcohol consumption was obtained at the time of transplant and 2 years after transplant in a prospective cohort study. Among 907 KTRs, 368 (40.6%) were drinkers at the time of transplant. Compared to non-drinkers, alcohol consumption did not affect the risk of death-censored graft failure (DCGF), biopsy-proven acute rejection (BPAR), cardiovascular events, or all-cause mortality. Compared to persistent non-drinkers, the development of DCGF, BPAR, cardiovascular events, all-cause mortality, or posttransplant diabetes mellitus was not affected by the alcohol consumption pattern (persistent, de novo, or stopped drinking) over time. However, de novo drinkers had a significantly higher total cholesterol (p < 0.001) and low-density lipoprotein cholesterol levels (p = 0.005) compared to persistent non-drinkers 5 years after transplant, and had significantly higher total cholesterol levels (p = 0.002) compared to the stopped drinking group 7 years after transplant, even after adjusting for the use of lipid-lowering agents, age, sex, and body mass index. Although pretransplant and posttransplant alcohol consumption were not associated with major outcomes in KTRs during the median follow-up of 6.0 years, a new start of alcohol use after KT results in a relatively poor lipid profile. | - |
dc.language | 영어 | - |
dc.publisher | Blackwell Publishing Inc. | - |
dc.title | Pretransplant and Posttransplant Alcohol Consumption and Outcomes in Kidney Transplantation: A Prospective Multicenter Cohort Study | - |
dc.type | Article | - |
dc.identifier.doi | 10.3389/ti.2022.10243 | - |
dc.citation.journaltitle | Transplant International | - |
dc.identifier.wosid | 000822717200001 | - |
dc.identifier.scopusid | 2-s2.0-85132082150 | - |
dc.citation.startpage | 10243 | - |
dc.citation.volume | 35 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Ahn, Curie | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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