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Effects of leucine-rich protein supplements in older adults with sarcopenia: A systematic review and meta-analysis of randomized controlled trials
DC Field | Value | Language |
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dc.contributor.author | Lee, Sang Yoon | - |
dc.contributor.author | Lee, Hyun Jeong | - |
dc.contributor.author | Lim, Jae-Young | - |
dc.date.accessioned | 2022-09-29T03:17:31Z | - |
dc.date.available | 2022-09-29T03:17:31Z | - |
dc.date.created | 2022-07-28 | - |
dc.date.issued | 2022-09 | - |
dc.identifier.citation | Archives of Gerontology and Geriatrics, Vol.102, p. 104758 | - |
dc.identifier.issn | 0167-4943 | - |
dc.identifier.uri | https://hdl.handle.net/10371/184573 | - |
dc.description.abstract | © 2022 Elsevier B.V.Objectives: This study examined whether leucine-rich protein supplements improve muscle strength, mass, and performance in sarcopenic older adults. Methods: We searched PubMed-Medline, Embase, and Cochrane Library databases for randomized controlled trials comparing leucine-rich protein supplements with a control intervention in sarcopenic older adults. A pairwise meta-analysis using a fixed-effects model was performed. The primary outcome of interest was muscle strength regardless of the measures used. Effect sizes were computed as standardized mean differences (SMDs) with 95% confidence intervals (CIs). Results: Six randomized controlled trials including a total of 699 participants were retrieved. Leucine-rich protein supplements improved participants overall muscle strength, mass, and performance compared to the control group (SMD = 0.939; 95% CI, 0.440–1.438; P < 0.001). As the primary outcome, muscle strength improved significantly in the leucine group (SMD = 0.794; 95% CI, 0.104–1.485; P = 0.024). Conclusion: Leucine-rich protein supplements improve muscle strength in sarcopenic older adults. They may be suggested in nutritional treatment of sarcopenia. | - |
dc.language | 영어 | - |
dc.publisher | Elsevier BV | - |
dc.title | Effects of leucine-rich protein supplements in older adults with sarcopenia: A systematic review and meta-analysis of randomized controlled trials | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.archger.2022.104758 | - |
dc.citation.journaltitle | Archives of Gerontology and Geriatrics | - |
dc.identifier.scopusid | 2-s2.0-85132913538 | - |
dc.citation.startpage | 104758 | - |
dc.citation.volume | 102 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Lim, Jae-Young | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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