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Nitrates vs. Other Types of Vasodilators and Clinical Outcomes in Patients with Vasospastic Angina: A Propensity Score-Matched Analysis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hyun-Jin | - |
dc.contributor.author | Jo, Sang-Ho | - |
dc.contributor.author | Lee, Min-Ho | - |
dc.contributor.author | Seo, Won-Woo | - |
dc.contributor.author | Kim, Hack-Lyoung | - |
dc.contributor.author | Lee, Kwan Yong | - |
dc.contributor.author | Yang, Tae-Hyun | - |
dc.contributor.author | Her, Sung-Ho | - |
dc.contributor.author | Lee, Byoung-Kwon | - |
dc.contributor.author | Park, Keun-Ho | - |
dc.contributor.author | Ahn, Youngkeun | - |
dc.contributor.author | Rha, Seung-Woon | - |
dc.contributor.author | Gwon, Hyeon-Cheol | - |
dc.contributor.author | Choi, Dong-Ju | - |
dc.contributor.author | Baek, Sang Hong | - |
dc.date.accessioned | 2022-09-29T03:18:11Z | - |
dc.date.available | 2022-09-29T03:18:11Z | - |
dc.date.created | 2022-07-13 | - |
dc.date.issued | 2022-06 | - |
dc.identifier.citation | Journal of Clinical Medicine, Vol.11 No.12, p. 3250 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://hdl.handle.net/10371/184626 | - |
dc.description.abstract | Although vasodilators are widely used in patients with vasospastic angina (VA), few studies have compared the long-term prognostic effects of different types of vasodilators. We investigated the long-term effects of vasodilators on clinical outcomes in VA patients according to the type of vasodilator used. Study data were obtained from a prospective multicenter registry that included patients who had symptoms suggestive of VA. Patients were classified into two groups according to use of nitrates (n = 239) or other vasodilators (n = 809) at discharge. The composite clinical events rate, including acute coronary syndrome (ACS), cardiac death, new-onset arrhythmia (including ventricular tachycardia and ventricular fibrillation), and atrioventricular block, was significantly higher in the nitrates group (5.3% vs. 2.2%, p = 0.026) during one year of follow-up. Specifically, the prevalence of ACS was significantly more frequent in the nitrates group (4.3% vs. 1.5%, p = 0.024). After propensity score matching, the adverse effects of nitrates remained. In addition, the use of nitrates at discharge was independently associated with a 2.69-fold increased risk of ACS in VA patients. In conclusion, using nitrates as a vasodilator at discharge can increase the adverse clinical outcomes in VA patients at one year of follow-up. Clinicians need to be aware of the prognostic value and consider prescribing other vasodilators. | - |
dc.language | 영어 | - |
dc.publisher | MDPI AG | - |
dc.title | Nitrates vs. Other Types of Vasodilators and Clinical Outcomes in Patients with Vasospastic Angina: A Propensity Score-Matched Analysis | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/jcm11123250 | - |
dc.citation.journaltitle | Journal of Clinical Medicine | - |
dc.identifier.wosid | 000816348900001 | - |
dc.identifier.scopusid | 2-s2.0-85131295924 | - |
dc.citation.number | 12 | - |
dc.citation.startpage | 3250 | - |
dc.citation.volume | 11 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Hack-Lyoung | - |
dc.contributor.affiliatedAuthor | Choi, Dong-Ju | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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