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Current Status of Low-Density Lipoprotein Cholesterol Target Achievement in Patients with Type 2 Diabetes Mellitus in Korea Compared with Recent Guidelines
DC Field | Value | Language |
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dc.contributor.author | Yun, Soo Jin | - |
dc.contributor.author | Jeong, In-Kyung | - |
dc.contributor.author | Cha, Jin-Hye | - |
dc.contributor.author | Lee, Juneyoung | - |
dc.contributor.author | Cho, Ho Chan | - |
dc.contributor.author | Choi, Sung Hee | - |
dc.contributor.author | Chun, SungWan | - |
dc.contributor.author | Jeon, Hyun Jeong | - |
dc.contributor.author | Kang, Ho-Cheol | - |
dc.contributor.author | Kim, Sang Soo | - |
dc.contributor.author | Ko, Seung-Hyun | - |
dc.contributor.author | Koh, Gwanpyo | - |
dc.contributor.author | Kwon, Su Kyoung | - |
dc.contributor.author | Lee, Jae Hyuk | - |
dc.contributor.author | Moon, Min Kyong | - |
dc.contributor.author | Noh, Junghyun | - |
dc.contributor.author | Park, Cheol-Young | - |
dc.contributor.author | Kim, Sungrae | - |
dc.date.accessioned | 2022-09-30T05:53:28Z | - |
dc.date.available | 2022-09-30T05:53:28Z | - |
dc.date.created | 2022-07-13 | - |
dc.date.issued | 2022-05 | - |
dc.identifier.citation | Diabetes and Metabolism Journal, Vol.46 No.3, pp.464-475 | - |
dc.identifier.issn | 2233-6079 | - |
dc.identifier.uri | https://hdl.handle.net/10371/184925 | - |
dc.description.abstract | Background: We evaluated the achievement of low-density lipoprotein cholesterol (LDL-C) targets in patients with type 2 diabetes mellitus (T2DM) according to up-to-date Korean Diabetes Association (KDA), European Society of Cardiology (ESC)/European Atherosclerosis Society (EAS), and American Diabetes Association (ADA) guidelines. Methods: This retrospective cohort study collected electronic medical record data from patients with T2DM (>_20 years) managed by endocrinologists from 15 hospitals in Korea (January to December 2019). Patients were categorized according to guidelines to assess LDL-C target achievement. KDA (2019): Very High-I (atherosclerotic cardiovascular disease [ASCVD]) <70 mg/dL; Very High-II (target organ damage [TOD], or cardiovascular risk factors [CVRFs]) <70 mg/dL; high (others) <100 mg/dL. ESC/EAS (2019): Very High-I (ASCVD): <55 mg/dL; Very High-II (TOD or >_3-CVRF) <55 mg/dL; high (diabetes >_10 years without TOD plus any CVRF) <70 mg/dL; moderate (diabetes <10 years without CVRF) <100 mg/dL. ADA (2019): Very High-I (ASCVD); Very High-II (age >_40+ TOD, or any CVRF), for high intensity statin or statin combined with ezetimibe. Results: Among 2,000 T2DM patients (mean age 62.6 years; male 55.9%; mean glycosylated hemoglobin 7.2%) ASCVD prevalence was 24.7%. Of 1,455 (72.8%) patients treated with statins, 73.9% received monotherapy. According to KDA guidelines, LDLC target achievement rates were 55.2% in Very High-I and 34.9% in Very High-II patients. With ESC/EAS guidelines, target attainment rates were 26.6% in Very High-I, 15.7% in Very High-II, and 25.9% in high risk patients. Based on ADA guidelines, most patients (78.9%) were very-high risk; however, only 15.5% received high-intensity statin or combination therapy. Conclusion: According to current dyslipidemia management guidelines, LDL-C goal achievement remains suboptimal in Korean patients with T2DM. | - |
dc.language | 영어 | - |
dc.publisher | 대한당뇨병학회 | - |
dc.title | Current Status of Low-Density Lipoprotein Cholesterol Target Achievement in Patients with Type 2 Diabetes Mellitus in Korea Compared with Recent Guidelines | - |
dc.type | Article | - |
dc.identifier.doi | 10.4093/dmj.2021.0088 | - |
dc.citation.journaltitle | Diabetes and Metabolism Journal | - |
dc.identifier.wosid | 000812328500010 | - |
dc.identifier.scopusid | 2-s2.0-85131270412 | - |
dc.citation.endpage | 475 | - |
dc.citation.number | 3 | - |
dc.citation.startpage | 464 | - |
dc.citation.volume | 46 | - |
dc.identifier.kciid | ART002842306 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Moon, Min Kyong | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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