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Nonalcoholic Fatty Liver Disease and Risk of Early-Onset Vasomotor Symptoms in Lean and Overweight Premenopausal Women
DC Field | Value | Language |
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dc.contributor.author | Cho, Yoosun | - |
dc.contributor.author | Chang, Yoosoo | - |
dc.contributor.author | Choi, Hye Rin | - |
dc.contributor.author | Kang, Jeonggyu | - |
dc.contributor.author | Kwon, Ria | - |
dc.contributor.author | Lim, Ga-Young | - |
dc.contributor.author | Ahn, Jiin | - |
dc.contributor.author | Kim, Kye-Hyun | - |
dc.contributor.author | Kim, Hoon | - |
dc.contributor.author | Hong, Yun Soo | - |
dc.contributor.author | Zhao, Di | - |
dc.contributor.author | Rampal, Sanjay | - |
dc.contributor.author | Cho, Juhee | - |
dc.contributor.author | Park, Hyun-Young | - |
dc.contributor.author | Guallar, Eliseo | - |
dc.contributor.author | Ryu, Seungho | - |
dc.date.accessioned | 2022-09-30T05:54:03Z | - |
dc.date.available | 2022-09-30T05:54:03Z | - |
dc.date.created | 2022-08-16 | - |
dc.date.issued | 2022-07 | - |
dc.identifier.citation | Nutrients, Vol.14 No.14 | - |
dc.identifier.issn | 2072-6643 | - |
dc.identifier.uri | https://hdl.handle.net/10371/184973 | - |
dc.description.abstract | The role of nonalcoholic fatty liver disease (NAFLD) in vasomotor symptom (VMS) risk in premenopausal women is unknown. We examined the prevalence of early-onset VMSs according to NAFLD status in lean and overweight premenopausal women. This cross-sectional study included 4242 premenopausal Korean women (mean age 45.4 years). VMSs (hot flashes and night sweats) were assessed using the Korean version of the Menopause-Specific Quality of Life questionnaire. Hepatic steatosis was determined using liver ultrasound; lean was defined as a body mass index of <23 kg/m(2). Participants were categorized into four groups: NAFLD-free lean (reference), NAFLD-free overweight, lean NAFLD, and overweight NAFLD. Compared with the reference, the multivariable-adjusted prevalence ratios (PRs) (95% confidence intervals (CIs)) for VMSs in NAFLD-free overweight, lean NAFLD, and overweight NAFLD were 1.22 (1.06-1.41), 1.38 (1.06-1.79), and 1.49 (1.28-1.73), respectively. For moderate-to-severe VMSs, the multivariable-adjusted PRs (95% CIs) comparing NAFLD-free overweight, lean NAFLD, and overweight NAFLD to the reference were 1.38 (1.10-1.74), 1.73 (1.16-2.57), and 1.74 (1.37-2.21), respectively. NAFLD, even lean NAFLD, was significantly associated with an increased risk of prevalent early-onset VMSs and their severe forms among premenopausal women. Further studies are needed to determine the longitudinal association between NAFLD and VMS risk. | - |
dc.language | 영어 | - |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | - |
dc.title | Nonalcoholic Fatty Liver Disease and Risk of Early-Onset Vasomotor Symptoms in Lean and Overweight Premenopausal Women | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/nu14142805 | - |
dc.citation.journaltitle | Nutrients | - |
dc.identifier.wosid | 000831984100001 | - |
dc.identifier.scopusid | 2-s2.0-85135100188 | - |
dc.citation.number | 14 | - |
dc.citation.volume | 14 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Hoon | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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