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College of Medicine/School of Medicine (의과대학/대학원)
Dept. of Medicine (의학과)
Journal Papers (저널논문_의학과)
Clinical Impact of Empirical Antibiotic Therapy in Patients With Coronavirus Disease 2019 Requiring Oxygen Therapy
- Authors
- Park, Do Hyeon ; Lee, Chan Mi ; Chang, Euijin ; Kang, Chang Kyung ; Park, Wan Beom ; Kim, Nam Joong ; Choe, Pyoeng Gyun ; Oh, Myoung-Don
- Issue Date
- 2022-07
- Publisher
- 대한의학회
- Citation
- Journal of Korean Medical Science, Vol.37 No.29, p. e238
- Abstract
- Despite the low prevalence of secondary bacterial infection in coronavirus disease 2019 (COVID-19) patients, most of them were administered antibiotic therapy empirically. However, the prognostic impact of empirical antibiotic therapy has not been evaluated. We conducted retrospective propensity score-matched case-control study of 233 COVID-19 patients with moderate to severe illnesses who required oxygen therapy and evaluated whether empirical antibiotic therapy could improve clinical outcomes. Empirical antibiotic therapy did not improve clinical outcomes including length of stay, days with oxygen requirement, the proportion of patients with increased oxygen demand, the proportion of patients who required mechanical ventilation, and overall mortality. This finding implies that routine administration of antibiotics for the treatment of COVID-19 is not essential and should be restricted.
- ISSN
- 1011-8934
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