Publications
Detailed Information
Impact of NT-proBNP on prognosis of acute decompensated chronic heart failure versus de novo heart failure
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Se-Eun | - |
dc.contributor.author | Cho, Dong-Hyuk | - |
dc.contributor.author | Kim, Jang Young | - |
dc.contributor.author | Kang, Seok-Min | - |
dc.contributor.author | Cho, Myeong-Chan | - |
dc.contributor.author | Lee, Hae-Young | - |
dc.contributor.author | Choi, Dong-Ju | - |
dc.contributor.author | Jeon, Eun-Seok | - |
dc.contributor.author | Yoo, Byung-Su | - |
dc.date.accessioned | 2022-09-30T05:54:25Z | - |
dc.date.available | 2022-09-30T05:54:25Z | - |
dc.date.created | 2022-08-23 | - |
dc.date.issued | 2022-09 | - |
dc.identifier.citation | International Journal of Cardiology, Vol.363, pp.163-170 | - |
dc.identifier.issn | 0167-5273 | - |
dc.identifier.uri | https://hdl.handle.net/10371/185002 | - |
dc.description.abstract | Background: NT-pro B-type natriuretic peptide (NT-proBNP) is a powerful prognostic factor for acute heart failure. We investigated whether NT-proBNP levels differ based on the type of heart failure present. Methods: Using the Korean Acute Heart Failure Registry, a prospective, multicenter cohort, we categorized pa-tients into two groups: de novo heart failure (DNHF, n = 1617) and acute decompensated chronic heart failure (ADHF, n = 1212). NT-proBNP levels were measured on admission. The primary outcome was all-cause mor-tality, and the secondary outcomes were re-hospitalization for heart failure and a composite of all-cause mor-tality or re-hospitalization for heart failure at 90 days and 1 year. Results: NT-proBNP levels were significantly lower in patients with DNHF than in those with ADHF (median 4213 vs. 5523 ng/L, p < 0.001). Compared to patients with DNHF, patients with ADHF had a significantly worse prognosis for 1-year all-cause mortality (adjusted hazard ratio (HR) = 1.46 [95% confidence interval (CI) = 1.07-1.98], p = 0.017). A higher NT-proBNP level was associated with higher 1-year all-cause mortality for both heart failure types (adjusted HR = 2.00, p = 0.002 in ADHF; adjusted HR = 2.41, p = 0.003 in DNHF). However, all-cause mortality risk was always higher in patients with ADHF than in those with DNHF for any given NT-proBNP level. Conclusion: NT-proBNP levels are an important prognostic factor for both DNHF and ADHF. Notably, patients with ADHF had consistently higher risks than those with DNHF with the same NT-proBNP level for 1-year all -cause mortality. | - |
dc.language | 영어 | - |
dc.publisher | Elsevier BV | - |
dc.title | Impact of NT-proBNP on prognosis of acute decompensated chronic heart failure versus de novo heart failure | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.ijcard.2022.06.055 | - |
dc.citation.journaltitle | International Journal of Cardiology | - |
dc.identifier.wosid | 000836120500027 | - |
dc.identifier.scopusid | 2-s2.0-85133576152 | - |
dc.citation.endpage | 170 | - |
dc.citation.startpage | 163 | - |
dc.citation.volume | 363 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Lee, Hae-Young | - |
dc.contributor.affiliatedAuthor | Choi, Dong-Ju | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.