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Dietary antioxidant consumption and the risk of type 2 diabetes in South Korean adults: a prospective cohort study based on the Health Examinees study
DC Field | Value | Language |
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dc.contributor.author | Tan, Li-Juan | - |
dc.contributor.author | Hwang, Su Bin | - |
dc.contributor.author | Jun, Shinyoung | - |
dc.contributor.author | Joung, Hyojee | - |
dc.contributor.author | Shin, Sangah | - |
dc.date.accessioned | 2022-09-30T05:58:46Z | - |
dc.date.available | 2022-09-30T05:58:46Z | - |
dc.date.created | 2022-07-27 | - |
dc.date.issued | 2022-07 | - |
dc.identifier.citation | BMJ Open, Vol.12 No.7, p. e065073 | - |
dc.identifier.issn | 2044-6055 | - |
dc.identifier.uri | https://hdl.handle.net/10371/185074 | - |
dc.description.abstract | © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.OBJECTIVES: Antioxidants are common dietary compounds with multiple health benefits. This study aimed to identify the association between dietary antioxidant consumption and the incidence of type 2 diabetes (T2D) mellitus (defined using the Korean Diabetes Association criteria) in South Korean adults. DESIGN: Baseline and follow-up data from the Health Examinees (HEXA) study, a large-scale community-based genomic cohort study conducted in South Korea SETTING: A South Korean community. PARTICIPANTS: A total of 20 594 participants, aged 40-79 years, who participated in the baseline and follow-up surveys of the HEXA study were included. After an average of 5 years of follow-up, there were 332 men and 360 women with T2D. RESULTS: Participants with the highest total flavonoid consumption (Q5) had a lower risk of T2D (men: HR 0.63; 95% CI 0.42 to 0.93; p value for trend=0.0169; and women: HR 0.54; 95% CI 0.438 to 0.78; p value for trend=0.0001) than those with the lowest consumption (Q1). Dietary total antioxidant capacity was significantly inversely associated with the development of T2D mellitus in women participants alone (HR 0.58; 95% CI 0.40 to 0.83; p value for trend=0.0004). Stratified analyses according to age and body mass index (BMI) showed that dietary total flavonoid consumption and total antioxidant capacity had a negative association with the development of T2D in women aged >52 years and women with BMI >25 kg/m2. CONCLUSIONS: Dietary flavonoid consumption and total antioxidant capacity were associated with a lower risk of T2D in South Korean adults, especially in women aged >52 years and overweight. The findings of this study may provide reference data for the modification of dietary guidelines for South Koreans. | - |
dc.language | 영어 | - |
dc.publisher | BMJ Publishing Group | - |
dc.title | Dietary antioxidant consumption and the risk of type 2 diabetes in South Korean adults: a prospective cohort study based on the Health Examinees study | - |
dc.type | Article | - |
dc.identifier.doi | 10.1136/bmjopen-2022-065073 | - |
dc.citation.journaltitle | BMJ Open | - |
dc.identifier.wosid | 000824496500011 | - |
dc.identifier.scopusid | 2-s2.0-85133936320 | - |
dc.citation.number | 7 | - |
dc.citation.startpage | e065073 | - |
dc.citation.volume | 12 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Joung, Hyojee | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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