Hyperglycemia and Hypoglycemia Are Associated with In-Hospital Mortality among Patients with Coronavirus Disease 2019 Supported with Extracorporeal Membrane Oxygenation

Cited 0 time in Web of Science Cited 0 time in Scopus

Son, Kuk Hui; Kim, Woong-Han; Kwak, Jae Gun; Choi, Chang-Hyu; Lee, Seok In; Ko, Ui Won; Kim, Hyoung Soo; Lee, Haeyoung; Chung, Euy Suk; Kim, Jae-Bum; Jang, Woo Sung; Jung, Jae Seung; Kim, Jieon; Yoon, Young Kyung; Song, Seunghwan; Sung, Minji; Jang, Myung Hun; Kim, Young Sam; Jeong, In-Seok; Kim, Do Wan; Kim, Tae Yun; Kim, Soon Jin; Kim, Su Wan; Hong, Joonhwa; An, Hyungmi

Issue Date
Journal of Clinical Medicine, Vol.11 No.17
Metabolic abnormalities, such as preexisting diabetes or hyperglycemia or hypoglycemia during hospitalization aggravated the severity of COVID-19. We evaluated whether diabetes history, hyperglycemia before and during extracorporeal membrane oxygenation (ECMO) support, and hypoglycemia were risk factors for mortality in patients with COVID-19. This study included data on 195 patients with COVID-19, who were aged >= 19 years and were treated with ECMO. The proportion of patients with diabetes history among nonsurvivors was higher than that among survivors. Univariate Cox regression analysis showed that in-hospital mortality after ECMO support was associated with diabetes history, renal replacement therapy (RRT), and body mass index (BMI) < 18.5 kg/m(2). Glucose at admission >200 mg/dL and glucose levels before ventilator >200 mg/dL were not associated with in-hospital mortality. However, glucose levels before ECMO >200 mg/dL and minimal glucose levels during hospitalization 200 mg/dL before ECMO and minimal glucose <70 mg/dL during hospitalization remained risk factors for in-hospital mortality after adjustment for age, BMI, and RRT. In conclusion, glucose >200 mg/dL before ECMO and minimal glucose level <70 mg/dL during hospitalization were risk factors for in-hospital mortality among COVID-19 patients who underwent ECMO.
Files in This Item:
There are no files associated with this item.
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)Journal Papers (저널논문_의학과)
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)Journal Papers (저널논문_의학과)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.