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Actinopolymorphols E and F, pyrazine alkaloids from a marine sediment-derived bacterium Streptomyces sp
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Sohee | - |
dc.contributor.author | Hillman, Prima F. | - |
dc.contributor.author | Lee, Ji Young | - |
dc.contributor.author | Lee, Juri | - |
dc.contributor.author | Lee, Jihye | - |
dc.contributor.author | Cha, Sun-Shin | - |
dc.contributor.author | Oh, Dong-Chan | - |
dc.contributor.author | Nam, Sang-Jip | - |
dc.contributor.author | Fenical, William | - |
dc.date.accessioned | 2022-10-18T00:32:56Z | - |
dc.date.available | 2022-10-18T00:32:56Z | - |
dc.date.created | 2022-10-13 | - |
dc.date.issued | 2022-11 | - |
dc.identifier.citation | Journal of Antibiotics, Vol.75 No.11, pp.619-625 | - |
dc.identifier.issn | 0021-8820 | - |
dc.identifier.uri | https://hdl.handle.net/10371/186394 | - |
dc.description.abstract | HPLC-UV-guided fractionation of crude extract from the marine sediment-derived bacterium Streptomyces sp. CNP-944 has yielded two new pyrazine alkaloids, actinopolymorphols E and F (1 and 2), in addition to the previously reported biosynthetic product, actinopolymorphol G (3), and the known actinopolymorphol D (4). The chemical structures of 1-3 were determined based on the interpretation of the 1D, 2D NMR, and MS spectroscopic data. Compound 2 displayed weak antibacterial activities against Kocuria rhizophila, Bacillus subtilis, and Staphylococcus aureus with minimum inhibitory concentration (MIC) values of 16, 64, and 64 mu g ml(-1), respectively. | - |
dc.language | 영어 | - |
dc.publisher | Nature Publishing Group | - |
dc.title | Actinopolymorphols E and F, pyrazine alkaloids from a marine sediment-derived bacterium Streptomyces sp | - |
dc.type | Article | - |
dc.identifier.doi | 10.1038/s41429-022-00562-2 | - |
dc.citation.journaltitle | Journal of Antibiotics | - |
dc.identifier.wosid | 000854677300002 | - |
dc.identifier.scopusid | 2-s2.0-85138018197 | - |
dc.citation.endpage | 625 | - |
dc.citation.number | 11 | - |
dc.citation.startpage | 619 | - |
dc.citation.volume | 75 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Oh, Dong-Chan | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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