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Sperm DNA fragmentation in consecutive ejaculates from patients with cancer for sperm cryopreservation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Seul Ki | - |
dc.contributor.author | Paik, Haerin | - |
dc.contributor.author | Lee, Jung Ryeol | - |
dc.contributor.author | Jee, Byung Chul | - |
dc.date.accessioned | 2022-10-20T02:26:30Z | - |
dc.date.available | 2022-10-20T02:26:30Z | - |
dc.date.created | 2022-09-28 | - |
dc.date.created | 2022-09-28 | - |
dc.date.created | 2022-09-28 | - |
dc.date.created | 2022-09-28 | - |
dc.date.created | 2022-09-28 | - |
dc.date.created | 2022-09-28 | - |
dc.date.created | 2022-09-28 | - |
dc.date.created | 2022-09-28 | - |
dc.date.created | 2022-09-28 | - |
dc.date.issued | 2022-09 | - |
dc.identifier.citation | Clinical and Experimental Reproductive Medicine, Vol.49 No.3, pp.196-201 | - |
dc.identifier.issn | 2233-8233 | - |
dc.identifier.uri | https://hdl.handle.net/10371/186572 | - |
dc.description.abstract | © 2022 The Korean Society For Reproductive MedicineObjective: This prospective consecutive study investigated the variation in sperm DNA fragmentation (SDF) in multiple semen samples from patients with cancer. Methods: Eighty-one patients with various cancers underwent multiple semen collections on 3 consecutive days for sperm cryopreservation prior to cancer treatment. A commercial Halosperm kit was used to measure SDF. Within and between-subject coefficients of variation were estimated via random-effects analysis of variance to assess the consistency of semen parameters and SDF. Intraclass correlation coefficients (ICCs) were calculated to assess the magnitude of the between-subject component of variance relative to the total variance. Results: The volume of semen in the day-2 and day-3 samples was significantly lower compared with the day-1 sample. Most parameters showed high ICC values, suggesting that within-subject fluctuations were small relative to the between-subject variability. The highest ICC values were identified for the SDF (ICC, 0.68; 95% confidence interval [CI], 0.45–0.84) and semen volume (ICC, 0.67; 95% CI, 0.45–0.84). Conclusion: Our findings showed that repeated ejaculates from patients with cancer had stable SDF levels | - |
dc.language | 영어 | - |
dc.publisher | 대한생식의학회 | - |
dc.title | Sperm DNA fragmentation in consecutive ejaculates from patients with cancer for sperm cryopreservation | - |
dc.type | Article | - |
dc.identifier.doi | 10.5653/cerm.2022.05323 | - |
dc.citation.journaltitle | Clinical and Experimental Reproductive Medicine | - |
dc.identifier.wosid | 000862842600005 | - |
dc.identifier.scopusid | 2-s2.0-85137644544 | - |
dc.citation.endpage | 201 | - |
dc.citation.number | 3 | - |
dc.citation.startpage | 196 | - |
dc.citation.volume | 49 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Jee, Byung Chul | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | SEMEN PARAMETERS | - |
dc.subject.keywordPlus | MEN | - |
dc.subject.keywordPlus | FERTILITY | - |
dc.subject.keywordPlus | PREGNANCY | - |
dc.subject.keywordPlus | QUALITY | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordAuthor | Cryopreservation | - |
dc.subject.keywordAuthor | Dna fragmentation | - |
dc.subject.keywordAuthor | Fertility preservation | - |
dc.subject.keywordAuthor | Semen analysis | - |
dc.subject.keywordAuthor | Sperm | - |
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