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Association between Body Mass Index and Risk of Gastric Cancer by Anatomic and Histologic Subtypes in Over 500,000 East and Southeast Asian Cohort Participants
DC Field | Value | Language |
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dc.contributor.author | Jang, Jieun | - |
dc.contributor.author | Lee, Sangjun | - |
dc.contributor.author | Ko, Kwang-Pil | - |
dc.contributor.author | Abe, Sarah K. | - |
dc.contributor.author | Rahman, Md. Shafiur | - |
dc.contributor.author | Saito, Eiko | - |
dc.contributor.author | Islam, Md. Rashedul | - |
dc.contributor.author | Sawada, Norie | - |
dc.contributor.author | Shu, Xiao-Ou | - |
dc.contributor.author | Koh, Woon-Puay | - |
dc.contributor.author | Sadakane, Atsuko | - |
dc.contributor.author | Tsuji, Ichiro | - |
dc.contributor.author | Kim, Jeongseon | - |
dc.contributor.author | Oze, Isao | - |
dc.contributor.author | Nagata, Chisato | - |
dc.contributor.author | Tsugane, Shoichiro | - |
dc.contributor.author | Cai, Hui | - |
dc.contributor.author | Yuan, Jian-Min | - |
dc.contributor.author | Gao, Yu-Tang | - |
dc.contributor.author | Ozasa, Kotaro | - |
dc.contributor.author | Matsuyama, Sanae | - |
dc.contributor.author | Kanemura, Seiki | - |
dc.contributor.author | Shin, Aesun | - |
dc.contributor.author | Ito, Hidemi | - |
dc.contributor.author | Wada, Keiko | - |
dc.contributor.author | Sugawara, Yumi | - |
dc.contributor.author | Chen, Yu | - |
dc.contributor.author | Ahsan, Habibul | - |
dc.contributor.author | Boffetta, Paolo | - |
dc.contributor.author | Chia, Kee Seng | - |
dc.contributor.author | Matsuo, Keitaro | - |
dc.contributor.author | Qiao, You-Lin | - |
dc.contributor.author | Rothman, Nathaniel | - |
dc.contributor.author | Zheng, Wei | - |
dc.contributor.author | Inoue, Manami | - |
dc.contributor.author | Kang, Daehee | - |
dc.contributor.author | Park, Sue K. | - |
dc.date.accessioned | 2022-10-24T00:16:06Z | - |
dc.date.available | 2022-10-24T00:16:06Z | - |
dc.date.created | 2022-10-18 | - |
dc.date.issued | 2022-09 | - |
dc.identifier.citation | Cancer Epidemiology Biomarkers and Prevention, Vol.31 No.9, pp.1727-1734 | - |
dc.identifier.issn | 1055-9965 | - |
dc.identifier.uri | https://hdl.handle.net/10371/186612 | - |
dc.description.abstract | Background: This study was performed to investigate the association between body mass index (BMI) and gastric cancer in East and Southeast Asia where most of gastric cancer is non-cardia gastric cancer. Methods: On the basis of 8,997 gastric cancer cases among the Asia Cohort Consortium participants from China, Japan, Korea, and Singapore (N = 538,835), we assessed gastric cancer risk according to BMI by calculating hazard ratios (HR) and 95% confidence intervals (CI) using the Cox proportional hazard regression model. Results: A U-shaped associations between BMI and gastric cancer risk were observed. Gastric cancer risks in underweight group (< 18.5 kg/m(2)) and in obesity group (& GE;27.5 kg/m(2)) were higher than reference BMI group (23-24.9 kg/m(2); HR, 1.15; 95% CI, 1.05-1.25 for underweight; HR, 1.12; 95% CI, 1.03-1.22 for obesity, respectively). The associations of underweight and obesity with gastric cancer risk were consistent in the analyses for non-cardia gastric cancer, intestinal-type gastric cancer, and late-onset gastric cancer. No significant association of underweight and obesity with the risk of cardia gastric cancer, diffuse-type gastric cancer, and early-onset gastric cancer was observed. In addition, we found that the U-shaped association between BMI and gastric cancer risk remained in nonsmokers, while only underweight was related to increased gastric cancer risk in smokers. Conclusions: BMI has a U-shaped association with gastric cancer risk in East and Southeast Asian population, especially for the non-cardia gastric cancer, intestinal-type gastric cancer, and late-onset gastric cancer. Impact: Future studies with consideration of anatomic location and histology of gastric cancer are needed to establish the association of underweight as well as obesity with gastric cancer risk. | - |
dc.language | 영어 | - |
dc.publisher | American Association for Cancer Research | - |
dc.title | Association between Body Mass Index and Risk of Gastric Cancer by Anatomic and Histologic Subtypes in Over 500,000 East and Southeast Asian Cohort Participants | - |
dc.type | Article | - |
dc.identifier.doi | 10.1158/1055-9965.EPI-22-0051 | - |
dc.citation.journaltitle | Cancer Epidemiology Biomarkers and Prevention | - |
dc.identifier.wosid | 000863160800001 | - |
dc.identifier.scopusid | 2-s2.0-85137135467 | - |
dc.citation.endpage | 1734 | - |
dc.citation.number | 9 | - |
dc.citation.startpage | 1727 | - |
dc.citation.volume | 31 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Shin, Aesun | - |
dc.contributor.affiliatedAuthor | Kang, Daehee | - |
dc.contributor.affiliatedAuthor | Park, Sue K. | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
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