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Resistance exercise training-induced skeletal muscle strength provides protective effects on high-fat-diet-induced metabolic stress in mice
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hye Jin | - |
dc.contributor.author | Kim, Youn Ju | - |
dc.contributor.author | Kim, Il Yong | - |
dc.contributor.author | Seong, Je Kyung | - |
dc.date.accessioned | 2022-12-27T04:16:31Z | - |
dc.date.available | 2022-12-27T13:19:03Z | - |
dc.date.issued | 2022-12-02 | - |
dc.identifier.citation | Laboratory Animal Research, 38(1):36 | ko_KR |
dc.identifier.issn | 2233-7660 | - |
dc.identifier.uri | https://doi.org/10.1186/s42826-022-00145-0 | - |
dc.identifier.uri | https://hdl.handle.net/10371/187359 | - |
dc.description.abstract | Background
Resistance exercise training is known to improve metabolic disorders, such as obesity and type2 diabetes. In this study, we investigated whether the beneficial effects of resistance exercise training persisted even after the discontinuation of training with high-fat diet (HFD)-induced metabolic stress. We further evaluated whether the improvement in skeletal muscle strength and endurance by training were correlated with improved metabolism. Eight-week-old male C57BL/6N mice were divided into groups that remained sedentary or had access to daily resistance exercise via ladder climbing for 8weeks. Trained and untrained mice were fed an HFD for 1week after the exercise training intervention (n = 5–8 per group). Results Resistance exercise-trained mice had a lean phenotype and counteracted diet-induced obesity and glucose tolerance, even after exercise cessation. Grip strength was significantly inversely correlated with the body weight, fat mass, and glucose tolerance. However, hanging time was significantly inversely correlated with body weight only. Conclusions These results have strong implications for the preventive effect of resistance exercise-induced metabolic improvement by enhancing skeletal muscle strength rather than endurance. | ko_KR |
dc.description.sponsorship | This work was supported by the Korea Mouse Phenotyping Project (NRF-2013M3A9D5072550) of the Ministry of Science, and ICT, through the National Research Foundation. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | BMC | ko_KR |
dc.subject | Resistance exercise | - |
dc.subject | Skeletal muscle | - |
dc.subject | Obesity | - |
dc.subject | Insulin sensitivity | - |
dc.subject | High-fat diet | - |
dc.title | Resistance exercise training-induced skeletal muscle strength provides protective effects on high-fat-diet-induced metabolic stress in mice | ko_KR |
dc.type | Article | ko_KR |
dc.identifier.doi | 10.1186/s42826-022-00145-0 | ko_KR |
dc.citation.journaltitle | Laboratory Animal Research | ko_KR |
dc.language.rfc3066 | en | - |
dc.rights.holder | The Author(s) | - |
dc.date.updated | 2022-12-04T04:13:41Z | - |
dc.citation.number | 1 | ko_KR |
dc.citation.startpage | 36 | ko_KR |
dc.citation.volume | 38 | ko_KR |
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