Use of imatinib mesylate in a cat with gastrointestinal stromal tumour

Abstract

A two-year-old, Turkish Angora, neutered male cat was evaluated for acute onset of melena and anaemia. A mass was identified in the duodenum and was diagnosed as gastrointestinal stromal tumour (GIST) through immunohistochemistry. The cat developed suspected nephropathy after 12 months of imatinib treatment for GIST. Imatinib was discontinued, but the patient died after two months due to renal failure. GIST is a rare neoplasm in cats, and treatment with imatinib in feline GIST has not been previously reported. © British Veterinary Association 2019. No commercial re-use. See rights and permissions. Published by BMJ.