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Bacteriophage application to control the contaminated water with Shigella
Cited 35 time in
Web of Science
Cited 36 time in Scopus
- Authors
- Issue Date
- 2016-03
- Publisher
- Nature Publishing Group
- Citation
- Scientific Reports, Vol.6, p. 22636
- Abstract
- Shigella is one of the most important waterborne and foodborne pathogens around the world. Emergence of antibiotic-resistant Shigella has made the development of alternatives to conventional antibiotics necessary. In this study, a virulent Myoviridae bacteriophage, pSs-1 was isolated from environmental water in South Korea and showed infectivity to S. flexneri as well as S. sonnei strains. One-step growth analysis showed that pSs-1 has a short latent period (25 min) and a large burst size (97 PFU/cell). According to the genomic analysis, pSs-1 contains 164,999 bp of genome with a G + C content of 35.54% and it is considered as a member of the T4-like bacteriophage group. These results showed that pSs-1 may have potential as a biocontrol agent instead of conventional antibiotics for shigellosis.
- ISSN
- 2045-2322
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