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Clinical Characteristics and Therapeutic Outcomes of Pediatric Blepharokeratoconjunctivitis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Moon, Jayoon | - |
dc.contributor.author | Lee, Junseok | - |
dc.contributor.author | Kim, Mee Kum | - |
dc.contributor.author | Hyon, Joon Young | - |
dc.contributor.author | Jeon, Hyun Sun | - |
dc.contributor.author | Oh, Joo Youn | - |
dc.date.accessioned | 2023-04-25T07:28:45Z | - |
dc.date.available | 2023-04-25T07:28:45Z | - |
dc.date.created | 2023-04-20 | - |
dc.date.created | 2023-04-20 | - |
dc.date.created | 2023-04-20 | - |
dc.date.created | 2023-04-20 | - |
dc.date.created | 2023-04-20 | - |
dc.date.created | 2023-04-20 | - |
dc.date.created | 2023-04-20 | - |
dc.date.created | 2023-04-20 | - |
dc.date.issued | 2023-05 | - |
dc.identifier.citation | Cornea, Vol.42 No.5, pp.578-583 | - |
dc.identifier.issn | 0277-3740 | - |
dc.identifier.uri | https://hdl.handle.net/10371/191449 | - |
dc.description.abstract | Purpose:The purpose of this study was to determine the clinical characteristics, disease course, therapeutic outcomes, and prognostic factors for pediatric patients with blepharokeratoconjunctivitis (BKC).Methods:A retrospective medical chart review was performed for patients aged 15 years or younger who had been diagnosed with BKC between 2004 and 2020 at 2 tertiary hospitals in Korea. The following data were collected: demographics, medical history, ocular findings, geometric profiling of corneal lesion, medical management, and outcomes.Results:A total of 137 patients (90 female and 47 male) were included. The patients' mean age was 8.3 ± 3.8 years at disease onset. Both eyes were involved in 57.7% of cases. The most common corneal lesion was corneal neovascularization (77.4%), followed by clinically visible corneal infiltration (51.8%) and stromal scarring (43.1%). Most of the corneal lesions involved a single quadrant, most commonly the inferior quadrant. After treatment, disease remission was achieved in 95% of patients, and visual acuities improved from 0.2 ± 0.3 logarithm of minimal angle of resolution at disease presentation to 0.1 ± 0.3 logarithm of minimal angle of resolution at final follow-up (P = 0.001). Recurrence occurred in 52.6% of patients. Cylinder power was significantly higher in patients with recurrence than in those without. The number of cases of recurrence was positively associated with final cylinder power.Conclusions:Although the treatment induced disease remission in 95% of children with BKC, recurrence occurred in 52.6% of those cases. Because recurrence resulted in significant astigmatism, careful observation for recurrence and prompt management are warranted for preservation of vision in pediatric patients with BKC. | - |
dc.language | 영어 | - |
dc.publisher | Lippincott Williams & Wilkins Ltd. | - |
dc.title | Clinical Characteristics and Therapeutic Outcomes of Pediatric Blepharokeratoconjunctivitis | - |
dc.type | Article | - |
dc.identifier.doi | 10.1097/ICO.0000000000003120 | - |
dc.citation.journaltitle | Cornea | - |
dc.identifier.wosid | 000961339300011 | - |
dc.identifier.scopusid | 2-s2.0-85151572556 | - |
dc.citation.endpage | 583 | - |
dc.citation.number | 5 | - |
dc.citation.startpage | 578 | - |
dc.citation.volume | 42 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Mee Kum | - |
dc.contributor.affiliatedAuthor | Hyon, Joon Young | - |
dc.contributor.affiliatedAuthor | Jeon, Hyun Sun | - |
dc.contributor.affiliatedAuthor | Oh, Joo Youn | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | CHILDREN | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordAuthor | astigmatism | - |
dc.subject.keywordAuthor | blepharokeratoconjunctivitis | - |
dc.subject.keywordAuthor | recurrence | - |
dc.subject.keywordAuthor | visual outcome | - |
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