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Clinical Application of the Standard Q COVID-19 Ag Test for the Detection of SARS-CoV-2 Infection

Cited 25 time in Web of Science Cited 26 time in Scopus

Oh, Sang-Min; Jeong, Hyeonju; Chang, Euijin; Choe, Pyoeng Gyun; Kang, Chang Kyung; Park, Wan Beom; Kim, Taek Soo; Kwon, Woon Yong; Oh, Myoung-Don; Kim, Nam Joong

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Journal of Korean Medical Science, Vol.36 No.14, pp.e101-5
We evaluated the Standard Q COVID-19 Ag test for the diagnosis of coronavirus disease 2019 (COVID-19) compared to the reverse transcription-polymerase chain reaction (RT-PCR) test. We applied both tests to patients who were about to be hospitalized, had visited an emergency room, or had been admitted due to COVID-19 confirmed by RT-PCR. Two nasopharyngeal swabs were obtained; one was tested by RT-PCR and the other by the Standard Q COVID-19 Ag test. A total of 118 pairs of tests from 98 patients were performed between January 5 and 11, 2021. The overall sensitivity and specificity for detecting severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) for the Standard Q COVID-19 Ag test compared to RT-PCR were 17.5% (95% confidence interval [CI], 8.8-32.0%) and 100% (95% CI, 95.3-100.0%). Analysis of the results using RT-PCR cycle thresholds of <= 30 or <= 25 increased the sensitivity to 26.9% (95% CI, 13.7- 46.1%), and 41.1% (95% CI, 21.6-64.0%), respectively.
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  • College of Medicine
  • Department of Medicine
Research Area Immunology, Infectious Diseases, Vaccination, 감염병, 바이러스질환, 예방접종


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