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Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Park, Hankum | - |
| dc.contributor.author | Koo, Ja Young | - |
| dc.contributor.author | Srikanth, Yellamelli V. V. | - |
| dc.contributor.author | Oh, Sangmi | - |
| dc.contributor.author | Lee, Jiyoon | - |
| dc.contributor.author | Park, Jongmin | - |
| dc.contributor.author | Park, Seung Bum | - |
| dc.date.accessioned | 2023-05-03T05:46:17Z | - |
| dc.date.available | 2023-05-03T05:46:17Z | - |
| dc.date.created | 2018-08-10 | - |
| dc.date.created | 2018-08-10 | - |
| dc.date.created | 2018-08-10 | - |
| dc.date.created | 2018-08-10 | - |
| dc.date.issued | 2016-04 | - |
| dc.identifier.citation | Chemical Communications, Vol.52 No.34, pp.5828-5831 | - |
| dc.identifier.issn | 1359-7345 | - |
| dc.identifier.uri | https://hdl.handle.net/10371/191805 | - |
| dc.description.abstract | Herein we report molecular shape-dependent nonspecific labeling of photoaffinity linkers (PLs) in the cellular proteome. Linear PLs have a greater tendency to engage in nonspecific binding than branched PLs. Exploiting this property, we discovered a smaller branched diazirine-based PL as the best photoaffinity probe with minimal nonspecific binding characteristics from among 5 probes with different PLs. | - |
| dc.language | 영어 | - |
| dc.publisher | Royal Society of Chemistry | - |
| dc.title | Nonspecific protein labeling of photoaffinity linkers correlates with their molecular shapes in living cells | - |
| dc.type | Article | - |
| dc.identifier.doi | 10.1039/c6cc01426g | - |
| dc.citation.journaltitle | Chemical Communications | - |
| dc.identifier.wosid | 000374396500012 | - |
| dc.identifier.scopusid | 2-s2.0-84966300008 | - |
| dc.citation.endpage | 5831 | - |
| dc.citation.number | 34 | - |
| dc.citation.startpage | 5828 | - |
| dc.citation.volume | 52 | - |
| dc.description.isOpenAccess | N | - |
| dc.contributor.affiliatedAuthor | Park, Hankum | - |
| dc.contributor.affiliatedAuthor | Park, Seung Bum | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.subject.keywordPlus | PHOTO-CROSS-LINKERS | - |
| dc.subject.keywordPlus | TARGET IDENTIFICATION | - |
| dc.subject.keywordPlus | BINDING PROTEINS | - |
| dc.subject.keywordPlus | PROBES | - |
| dc.subject.keywordPlus | DISCOVERY | - |
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