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Diffusion-weighted imaging for evaluating lymph node eradication after neoadjuvant chemoradiation therapy in locally advanced rectal cancer
DC Field | Value | Language |
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dc.contributor.author | Ryu, Kyeong Hwa | - |
dc.contributor.author | Kim, Seung Ho | - |
dc.contributor.author | Yoon, Jung-Hee | - |
dc.contributor.author | Lee, Yedaun | - |
dc.contributor.author | Paik, Jin Ho | - |
dc.contributor.author | Lim, Yun-Jung | - |
dc.contributor.author | Lee, Kwang Hwi | - |
dc.date.accessioned | 2023-05-08T00:42:43Z | - |
dc.date.available | 2023-05-08T00:42:43Z | - |
dc.date.created | 2018-09-14 | - |
dc.date.created | 2018-09-14 | - |
dc.date.issued | 2016-02 | - |
dc.identifier.citation | Acta Radiologica, Vol.57 No.2, pp.133-141 | - |
dc.identifier.issn | 0284-1851 | - |
dc.identifier.uri | https://hdl.handle.net/10371/191985 | - |
dc.description.abstract | Background: As lymph node (LN) eradication is the prerequisite for clinical surveillance or local excision for patients who have achieved a complete response after preoperative chemoradiation therapy (CRT), the radiological evaluation of LN eradication is important. Purpose: To evaluate the added value of diffusion-weighted imaging (DWI) in the evaluation of LN eradication after CRT in patients with locally advanced rectal cancer (LARC). Material and Methods: Ninety-five consecutive patients (64 men, 31 women; mean age, 59 years; range, 32-82 years) who underwent pre-and post-CRT 1.5-T MRI with DWI (b=0, 1000s/mm(2)) were enrolled. To evaluate the added value of DWI in the evaluation of LN eradication after CRT, two radiologists first independently read the pre-and post-CRT T2-weighted (T2W) images and then read the combined T2W imaging set and the pre-and post-CRT DWIs with a 4-week interval. The radiologists recorded their confidence scores for LN eradication using a 5-point scale on a per-patient basis. The diagnostic performances were compared between the two reading sessions for each reader with pair-wise comparisons of receiver-operating characteristic curves. Histopathological reports served as the reference standards for LN eradication. Results: The study population consisted of an LN-eradicated group (n=66) and a non-eradicated group (n=29). The diagnostic performances did not significantly differ between the two reading sessions for the two readers (AUCs for reader 1, 0.770 and 0.774, P=0.8155; for reader 2, 0.794 and 0.798, P=0.8588). Conclusion: Adding DWI to T2W imaging provided no additional diagnostic benefit for the evaluation of LN eradication following CRT in patients with LARC. | - |
dc.language | 영어 | - |
dc.publisher | Taylor & Francis | - |
dc.title | Diffusion-weighted imaging for evaluating lymph node eradication after neoadjuvant chemoradiation therapy in locally advanced rectal cancer | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/0284185114568908 | - |
dc.citation.journaltitle | Acta Radiologica | - |
dc.identifier.wosid | 000368909500004 | - |
dc.identifier.scopusid | 2-s2.0-84961786429 | - |
dc.citation.endpage | 141 | - |
dc.citation.number | 2 | - |
dc.citation.startpage | 133 | - |
dc.citation.volume | 57 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Paik, Jin Ho | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | PREOPERATIVE CHEMORADIOTHERAPY | - |
dc.subject.keywordPlus | COLORECTAL-CANCER | - |
dc.subject.keywordPlus | RESECTION MARGIN | - |
dc.subject.keywordPlus | MRI | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | RECURRENCE | - |
dc.subject.keywordPlus | ACCURACY | - |
dc.subject.keywordPlus | PATTERNS | - |
dc.subject.keywordPlus | EXCISION | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordAuthor | Diffusion-weighted image | - |
dc.subject.keywordAuthor | lymph node | - |
dc.subject.keywordAuthor | lymphatic metastasis | - |
dc.subject.keywordAuthor | rectum | - |
dc.subject.keywordAuthor | neoplasm | - |
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