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Apparent diffusion coefficient for lymph node characterization after chemoradiation therapy for locally advanced rectal cancer
DC Field | Value | Language |
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dc.contributor.author | Kim, Seung Ho | - |
dc.contributor.author | Ryu, Kyeong Hwa | - |
dc.contributor.author | Yoon, Jung-Hee | - |
dc.contributor.author | Lee, Yedaun | - |
dc.contributor.author | Paik, Jin Ho | - |
dc.contributor.author | Kim, Suk Jung | - |
dc.contributor.author | Jung, Hyun Kyung | - |
dc.contributor.author | Lee, Kwang Hwi | - |
dc.date.accessioned | 2023-05-08T00:42:58Z | - |
dc.date.available | 2023-05-08T00:42:58Z | - |
dc.date.created | 2018-10-04 | - |
dc.date.created | 2018-10-04 | - |
dc.date.issued | 2015-12 | - |
dc.identifier.citation | ACTA RADIOLOGICA, Vol.56 No.12, pp.1446-1453 | - |
dc.identifier.issn | 0284-1851 | - |
dc.identifier.uri | https://hdl.handle.net/10371/191990 | - |
dc.description.abstract | Background: Because further treatment plans depends on lymph node (LN) status after neoadjuvant chemoradiation therapy (CRT), the accurate characterization of LN is important. Purpose: To evaluate the diagnostic performance of apparent diffusion coefficient (ADC) for LN characterization after CRT and to compare the performance with that of LN size. Material and Methods: Fifty-three patients (36 men, 17 women; mean age, 58 years; age range, 34-79 years) who underwent CRT and subsequent surgery were included. All patients underwent 1.5-T magnetic resonance imaging (MRI). Each regional LN on post-CRT MRI was identified in consensus by two radiologists after reviewing the pre-CRT MRI. The ADC value and size in each LN was measured. To compare the mean ADC values and sizes of the metastatic and non-metastatic LNs after CRT, the t-test was used. To calculate the performance, a ROC curve analysis was performed. The histopathological examinations served as the reference standard. Results: A total of 115 LNs (29 metastatic and 86 non-metastatic) were matched and analyzed. The mean ADC of the metastatic LNs was significantly higher than that of the non-metastatic LNs (1.36 +/- 0.27 x 10(-3) mm(2)/s; 1.13 +/- 0.23 x 10(-3) mm(2)/s, P < 0.0001). The mean size of the metastatic LNs was also significantly larger than that of the non-metastatic LNs (5.6 +/- 3.1; 3.9 +/- 1.2, P = 0.0078). There was no significant difference between the areas under the curve of the ADC and size (0.742 [95% CI, 0.652-0.819]; 0.680 [0.586-0.764], respectively, P = 0.4090). Conclusion: The performance of ADC for LN characterization after CRT was comparable to that of LN size. | - |
dc.language | 영어 | - |
dc.publisher | SAGE PUBLICATIONS LTD | - |
dc.title | Apparent diffusion coefficient for lymph node characterization after chemoradiation therapy for locally advanced rectal cancer | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/0284185114560936 | - |
dc.citation.journaltitle | ACTA RADIOLOGICA | - |
dc.identifier.wosid | 000365400200007 | - |
dc.identifier.scopusid | 2-s2.0-84960497217 | - |
dc.citation.endpage | 1453 | - |
dc.citation.number | 12 | - |
dc.citation.startpage | 1446 | - |
dc.citation.volume | 56 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Paik, Jin Ho | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | NEOADJUVANT CHEMORADIATION | - |
dc.subject.keywordPlus | NONOPERATIVE TREATMENT | - |
dc.subject.keywordPlus | RADIATION-THERAPY | - |
dc.subject.keywordPlus | TUMOR RESPONSE | - |
dc.subject.keywordPlus | CHEMORADIOTHERAPY | - |
dc.subject.keywordPlus | MICROMETASTASIS | - |
dc.subject.keywordPlus | CHEMOTHERAPY | - |
dc.subject.keywordPlus | EXCISION | - |
dc.subject.keywordAuthor | Diffusion-weighted magnetic resonance imaging | - |
dc.subject.keywordAuthor | apparent diffusion coefficient | - |
dc.subject.keywordAuthor | lymph node | - |
dc.subject.keywordAuthor | lymphatic metastasis | - |
dc.subject.keywordAuthor | rectum | - |
dc.subject.keywordAuthor | neoplasm | - |
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