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Evaluation of lymph node metastases: Comparison of gadofluorine M-enhanced MRI and diffusion-weighted MRI in a rabbit VX2 rectal cancer model
DC Field | Value | Language |
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dc.contributor.author | Kim, Seung Ho | - |
dc.contributor.author | Lee, Jeong Min | - |
dc.contributor.author | Moon, Sung Kyoung | - |
dc.contributor.author | Chung, Yong Eun | - |
dc.contributor.author | Paik, Jin Ho | - |
dc.contributor.author | Choi, Seung Hong | - |
dc.contributor.author | Kim, Min Uk | - |
dc.contributor.author | Han, Joon Koo | - |
dc.contributor.author | Choi, Byung Ihn | - |
dc.date.accessioned | 2023-05-08T00:50:50Z | - |
dc.date.available | 2023-05-08T00:50:50Z | - |
dc.date.created | 2021-02-18 | - |
dc.date.created | 2021-02-18 | - |
dc.date.issued | 2012-05 | - |
dc.identifier.citation | Journal of Magnetic Resonance Imaging, Vol.35 No.5, pp.1179-1186 | - |
dc.identifier.issn | 1053-1807 | - |
dc.identifier.uri | https://hdl.handle.net/10371/192092 | - |
dc.description.abstract | Purpose: To compare the diagnostic performance of a diffusion-weighted imaging (DWI) dataset and a gadofluorine M-enhanced imaging dataset for identifying lymph node (LN) metastases in a rabbit rectal cancer model. Materials and Methods: VX2 carcinomas were injected into the rectum of 26 rabbits. Four weeks later, T2weighted imaging (T2WI), pre-T1WI, DWI, and post-T1WI were performed. Two radiologists independently reviewed the DWI set (T2WI, pre-T1WI, DWI) and the gadofluorine M set (T2WI, pre-and post-T1WI) and recorded their confidence scores for LN metastasis on a per-LN basis. Receiver operating characteristic (ROC) analysis was performed to compare the area under the ROC curve (Az) of the two imaging sets. Histopathologic results were used as the reference standard. Results: The Az and sensitivity of the gadofluorine M set were comparable to those of the DWI set (Az, for reader 1, 0.849, 0.829, P 0.571; for reader 2, 0.923, 0.876, P 0.212; sensitivity, for reader 1, 97%, 97%; for reader 2, 97%, 92%, P 0.304). The specificity of the former was greater than that of the latter (for reader 1, 65%, 53%, P 0.0003; for reader 2, 81%, 68%, P 0.01). Conclusion: Gadofluorine M-enhanced images provided greater specificity than DWI for identifying LN metastases, whereas the Az and sensitivity of the former were comparable to those of the latter. | - |
dc.language | 영어 | - |
dc.publisher | John Wiley & Sons Inc. | - |
dc.title | Evaluation of lymph node metastases: Comparison of gadofluorine M-enhanced MRI and diffusion-weighted MRI in a rabbit VX2 rectal cancer model | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/jmri.23513 | - |
dc.citation.journaltitle | Journal of Magnetic Resonance Imaging | - |
dc.identifier.wosid | 000302721800023 | - |
dc.identifier.scopusid | 2-s2.0-84859793688 | - |
dc.citation.endpage | 1186 | - |
dc.citation.number | 5 | - |
dc.citation.startpage | 1179 | - |
dc.citation.volume | 35 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Lee, Jeong Min | - |
dc.contributor.affiliatedAuthor | Paik, Jin Ho | - |
dc.contributor.affiliatedAuthor | Choi, Seung Hong | - |
dc.contributor.affiliatedAuthor | Han, Joon Koo | - |
dc.contributor.affiliatedAuthor | Choi, Byung Ihn | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | UTERINE CERVICAL-CANCER | - |
dc.subject.keywordPlus | SIZE | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | ACCURACY | - |
dc.subject.keywordPlus | CRITERIA | - |
dc.subject.keywordPlus | HEAD | - |
dc.subject.keywordAuthor | experimental study | - |
dc.subject.keywordAuthor | diffusion weighted magnetic resonance imaging | - |
dc.subject.keywordAuthor | gadofluorine M | - |
dc.subject.keywordAuthor | apparent diffusion coefficient | - |
dc.subject.keywordAuthor | lymph node | - |
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