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Extranodal NK/T Cell Lymphoma Accompanied by Heavy Eosinophilic Infiltration and Peripheral Blood Eosinophilia, Involving Skeletal Muscles

DC Field Value Language
dc.contributor.authorPaik, Jin Ho-
dc.contributor.authorJeon, Yoon Kyung-
dc.contributor.authorGo, Heounjeong-
dc.contributor.authorKim, Chul Woo-
dc.date.accessioned2023-05-08T00:51:44Z-
dc.date.available2023-05-08T00:51:44Z-
dc.date.created2021-06-21-
dc.date.created2021-06-21-
dc.date.issued2011-07-
dc.identifier.citationKorean Journal of Pathology, Vol.45, pp.S70-S74-
dc.identifier.issn1738-1843-
dc.identifier.urihttps://hdl.handle.net/10371/192110-
dc.description.abstractThe patient was a 52-year-old female with swelling in both lower legs and peripheral blood eosinophilia. Biopsy specimen revealed the heavy infiltration of eosinophils with sparse small lymphocytes showing mild atypia. The diagnosis was Kimura disease. The symptoms including eosinophilia were relieved by steroid treatment. At 17 months from initial biopsy, the patient developed swelling of the buttock. At 25 months, fever and dyspnea with multiple lung nodules developed. Wedge resection revealed multiple aggregates of CD3(+), CD56(+), Epstein-Barr virus(+) large atypical lymphocytes with necrosis. The patient was finally diagnosed with extranodal NK/T cell lymphoma (NKTL). Epstein-Barr virus in situ hybridization retrospectively performed on the previous biopsies demonstrated Epstein-Barr virus infection in small CD3(+) lymphocytes. The patient expired after 26 months despite chemotherapy. Blood eosinophilia correlated well with disease activity during the clinical course. This case shows not only unusual histologic features, which hampered the correct diagnosis, but also a unique clinical manifestation of NKTL.-
dc.language영어-
dc.publisherKorean Society of Pathologists-
dc.titleExtranodal NK/T Cell Lymphoma Accompanied by Heavy Eosinophilic Infiltration and Peripheral Blood Eosinophilia, Involving Skeletal Muscles-
dc.typeArticle-
dc.identifier.doi10.4132/KoreanJPathol.2011.45.S1.S70-
dc.citation.journaltitleKorean Journal of Pathology-
dc.identifier.wosid000293862400017-
dc.citation.endpageS74-
dc.citation.startpageS70-
dc.citation.volume45-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorPaik, Jin Ho-
dc.contributor.affiliatedAuthorJeon, Yoon Kyung-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.subject.keywordPlusEPSTEIN-BARR-VIRUS-
dc.subject.keywordPlusKIMURAS-DISEASE-
dc.subject.keywordPlusNASAL-TYPE-
dc.subject.keywordPlusIL-5-
dc.subject.keywordPlusDIFFERENTIATION-
dc.subject.keywordPlusINTERLEUKIN-5-
dc.subject.keywordPlusINFLAMMATION-
dc.subject.keywordPlusEXPRESSION-
dc.subject.keywordAuthorLymphoma, extranodal NK/T cell-
dc.subject.keywordAuthorAngiolymphoid hyperplasia with eosinophilia-
dc.subject.keywordAuthorEosinophilia-
dc.subject.keywordAuthorEpstein-Barr virus infections-
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Paik, Jin Ho Image

Paik, Jin Ho백진호
(기금)부교수
  • College of Medicine
  • Department of Medicine
Research Area Head and Neck Pathology, Hematopathology, Renal Pathology, 두경부병리학, 신장병리학, 혈액병리학

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