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New azaspiracids in Amphidomataceae (Dinophyceae)
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Krock, Bernd | - |
dc.contributor.author | Tillmann, Urban | - |
dc.contributor.author | Voss, Daniela | - |
dc.contributor.author | Koch, Boris P. | - |
dc.contributor.author | Salas, Rafael | - |
dc.contributor.author | Witt, Matthias | - |
dc.contributor.author | Potvin, Eric | - |
dc.contributor.author | Jeong, Hae Jin | - |
dc.date.accessioned | 2023-06-08T07:51:22Z | - |
dc.date.available | 2023-06-08T07:51:22Z | - |
dc.date.created | 2021-03-19 | - |
dc.date.created | 2021-03-19 | - |
dc.date.issued | 2012-10 | - |
dc.identifier.citation | Toxicon, Vol.60 No.5, pp.830-839 | - |
dc.identifier.issn | 0041-0101 | - |
dc.identifier.uri | https://hdl.handle.net/10371/192724 | - |
dc.description.abstract | Azaspiracids (AZAs) are a group of lipophilic polyether toxins implicated in incidents of shellfish poisoning in humans, particularly in northern Europe, which are produced by the small marine dinoflagellate Azadinium spinosum. Other related species/strains of the Amphidomataceae have not been proven to date to contain any of the known azaspiracids. Closer analyses of these species/strains by triple quadrupole mass spectrometry in the precursor and product ion mode now revealed four new compounds with high similarity to azaspiracids, all of them with a characteristic rn/z 348 fragment but with absence of the m/z 362 fragment. These compounds were detected in three species/strains, i.e. in North Sea isolates of Azadinium poporum (molecular mass: 845.5 Da), in a Korean isolate which has been designated as A. cf. poporum (molecular mass: 857.5 Da) and in Amphidoma languida isolated from Bantry Bay, Ireland (molecular masses: 815.5 and 829.5 Da). Cell quotas of roughly 2-20 fg per cell were in the same range as found for AZA-1/-2 in A. spinosum. Structures for all compounds were proposed by interpretation of fragmentation patterns and high resolution mass measurements using Fourier transform ion cyclotron resonance-mass spectrometry (FTICR-MS). (C) 2012 Elsevier Ltd. All rights reserved. | - |
dc.language | 영어 | - |
dc.publisher | Pergamon Press | - |
dc.title | New azaspiracids in Amphidomataceae (Dinophyceae) | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.toxicon.2012.05.007 | - |
dc.citation.journaltitle | Toxicon | - |
dc.identifier.wosid | 000308121400015 | - |
dc.identifier.scopusid | 2-s2.0-84863488452 | - |
dc.citation.endpage | 839 | - |
dc.citation.number | 5 | - |
dc.citation.startpage | 830 | - |
dc.citation.volume | 60 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Jeong, Hae Jin | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | DINOFLAGELLATE GENUS AZADINIUM | - |
dc.subject.keywordPlus | TRAP MASS-SPECTROMETRY | - |
dc.subject.keywordPlus | MYTILUS-EDULIS | - |
dc.subject.keywordPlus | SHELLFISH | - |
dc.subject.keywordPlus | ANALOGS | - |
dc.subject.keywordPlus | MUSSELS | - |
dc.subject.keywordPlus | TOXINS | - |
dc.subject.keywordPlus | BIOSYNTHESIS | - |
dc.subject.keywordPlus | CONFIRMATION | - |
dc.subject.keywordPlus | POPORUM | - |
dc.subject.keywordAuthor | Azaspiracids | - |
dc.subject.keywordAuthor | Azadinium poporum | - |
dc.subject.keywordAuthor | Amphidoma languida | - |
dc.subject.keywordAuthor | LC-MS/MS | - |
dc.subject.keywordAuthor | Phycotoxin | - |
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- College of Natural Sciences
- Department of Earth and Environmental Sciences
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