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Comparative study of the ocular irritation potential of various alkyl polyglucoside surfactants
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Sun-A | - |
dc.contributor.author | Han, Ju-Hee | - |
dc.contributor.author | An, Susun | - |
dc.contributor.author | Lee, Key Hyun | - |
dc.contributor.author | Park, Jae-Hak | - |
dc.contributor.author | Kim, Han Kon | - |
dc.contributor.author | Lee, Tae Ryong | - |
dc.date.accessioned | 2023-07-07T08:01:38Z | - |
dc.date.available | 2023-07-07T08:01:38Z | - |
dc.date.created | 2021-12-21 | - |
dc.date.issued | 2010-03 | - |
dc.identifier.citation | Cutaneous and Ocular Toxicology, Vol.29 No.1, pp.50-56 | - |
dc.identifier.issn | 1556-9527 | - |
dc.identifier.uri | https://hdl.handle.net/10371/194823 | - |
dc.description.abstract | In the present work, we assessed the relationship between alkyl carbon chain length and ocular irritation potentials using the hen's egg test-chorioallantoic membrane (HET-CAM) and bovine corneal opacity and permeability (BCOP) assays using 5 commercial alkyl polyglucoside surfactants with different compositions of alkyl chain lengths (C6-C16). With HET-CAM, there was a good correlation between the proportion of C(10) alkyl polyglucoside and the eye irritation potential Q score (r(2) = 0.912, p = .011). There were no significant differences between the proportion of C(10) alkyl polyglucoside and corneal opacity in BCOP assays; however, there was a relatively high positive correlation between the proportion of C(10) alkyl carbon chain lengths and corneal permeability (r(2) = 0.736, p = .063).. | - |
dc.language | 영어 | - |
dc.publisher | Taylor & Francis | - |
dc.title | Comparative study of the ocular irritation potential of various alkyl polyglucoside surfactants | - |
dc.type | Article | - |
dc.identifier.doi | 10.3109/15569520903471640 | - |
dc.citation.journaltitle | Cutaneous and Ocular Toxicology | - |
dc.identifier.wosid | 000274856100009 | - |
dc.identifier.scopusid | 2-s2.0-77149157804 | - |
dc.citation.endpage | 56 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 50 | - |
dc.citation.volume | 29 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Park, Jae-Hak | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | PERMEABILITY BCOP ASSAY | - |
dc.subject.keywordPlus | BOVINE CORNEAL OPACITY | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | EYE | - |
dc.subject.keywordPlus | FORMULATIONS | - |
dc.subject.keywordPlus | INGREDIENTS | - |
dc.subject.keywordPlus | PRODUCTS | - |
dc.subject.keywordPlus | TESTS | - |
dc.subject.keywordPlus | SKIN | - |
dc.subject.keywordAuthor | Alkyl chain length | - |
dc.subject.keywordAuthor | Alkyl polyglucoside | - |
dc.subject.keywordAuthor | BCOP | - |
dc.subject.keywordAuthor | Eye or ocular irritation potential | - |
dc.subject.keywordAuthor | HET-CAM | - |
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