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Association between Type A blaZ Gene Polymorphism and Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Sun Hee | - |
dc.contributor.author | Park, Wan Beom | - |
dc.contributor.author | Lee, Shinwon | - |
dc.contributor.author | Park, Sohee | - |
dc.contributor.author | Kim, Shin Woo | - |
dc.contributor.author | Lee, Jong-Myung | - |
dc.contributor.author | Chang, Hyun Ha | - |
dc.contributor.author | Kwon, Ki Tae | - |
dc.contributor.author | Choe, Pyoeng Gyun | - |
dc.contributor.author | Kim, Nam Joong | - |
dc.contributor.author | Kim, Hong Bin | - |
dc.contributor.author | Oh, Myoung-Don | - |
dc.date.accessioned | 2024-04-26T01:05:11Z | - |
dc.date.available | 2024-04-26T01:05:11Z | - |
dc.date.created | 2018-09-03 | - |
dc.date.issued | 2016-11 | - |
dc.identifier.citation | Antimicrobial Agents and Chemotherapy, Vol.60 No.11, pp.6928-6932 | - |
dc.identifier.issn | 0066-4804 | - |
dc.identifier.uri | https://hdl.handle.net/10371/199683 | - |
dc.description.abstract | Some proportion of type A blaZ gene-positive methicillin-susceptible Staphylococcus aureus strains exhibit the cefazolin inoculum effect (CIE). The type A blaZ gene was divided into two groups by single nucleotide polymorphisms (SNPs) at Ser226Pro and Cys229Tyr. The median cefazolin MICs at a high inoculum concentration were 5.69 mu/ml for the Ser-Cys group and 40.32 mu/ml for the Pro-Tyr group (P = 0.01). The SNPs at codons 226 and 229 in the amino acid sequence encoded by the blaZ gene were closely associated with the CIE. | - |
dc.language | 영어 | - |
dc.publisher | American Society for Microbiology | - |
dc.title | Association between Type A blaZ Gene Polymorphism and Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus | - |
dc.type | Article | - |
dc.identifier.doi | 10.1128/AAC.01517-16 | - |
dc.citation.journaltitle | Antimicrobial Agents and Chemotherapy | - |
dc.identifier.wosid | 000389063500063 | - |
dc.identifier.scopusid | 2-s2.0-84994528699 | - |
dc.citation.endpage | 6932 | - |
dc.citation.number | 11 | - |
dc.citation.startpage | 6928 | - |
dc.citation.volume | 60 | - |
dc.description.isOpenAccess | Y | - |
dc.contributor.affiliatedAuthor | Park, Wan Beom | - |
dc.contributor.affiliatedAuthor | Kim, Nam Joong | - |
dc.contributor.affiliatedAuthor | Kim, Hong Bin | - |
dc.contributor.affiliatedAuthor | Oh, Myoung-Don | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | BETA-LACTAMASE | - |
dc.subject.keywordPlus | ENDOCARDITIS | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | OXACILLIN | - |
dc.subject.keywordPlus | VARIANTS | - |
dc.subject.keywordPlus | SEQUENCE | - |
dc.subject.keywordPlus | THERAPY | - |
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