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Clinical evaluations of OSTEON (R) as a new alloplastic material in sinus bone grafting and its effect on bone healing

Cited 27 time in Web of Science Cited 35 time in Scopus
Authors

Kim, Young Kyun; Yun, Pil Young; Lim, Sung Chul; Kim, Su Gwan; Lee, Hyo Jung; Ong, Joo L.

Issue Date
2008-07
Publisher
John Wiley & Sons Inc.
Citation
Journal of Biomedical Materials Research - Part B Applied Biomaterials, Vol.86B No.1, pp.270-277
Abstract
Purpose: The objective of this study was to clinically evaluate the use of OSTEON(R) as a sinus graft material and to measure the effect of healing at 4 and 6 months after surgery. Materials and Methods: After sinus graft using OSTEON(R) in 17 patients, bone specimens were collected from lateral sinus using 2.0-mm trephine bur at the time of 4 or 6 months after surgery. Histology of the bone specimens was prepared and the percentage of newly formed bone fraction, lamellar bone/woven bone ratio (LB/WB), and newly formed bone/graft material ratio (NB/GM) were measured to indicate the suitability of the materials and the successful healing of the graft. Results: The morphology of OSTEON(R) was observed to be interconnected, with 77% porosity and a pore size of 300-500 mu m. After implantation, the mean percentage of newly formed bone fraction after 4 months and 6 months surgery was 40.6 and 51.9%, respectively. Statistical analysis indicated no significant difference (p = 0.135) in the newly formed bone fraction between the two postoperative periods. The mean LB/WB ratio after 4 months and 6 months surgery was 0.14 and 0.45, respectively, with significant difference observed between the two postoperative periods (p = 0.027). Additionally, the mean NB/GM ratio after 4 months and 6 months surgery was 1.95 and 7.72, respectively, with significant difference observed between the two postoperative periods (p = 0.046). Conclusion: It was concluded that OSTEON(R) is suitable for use in sinus graft application since desirable time-dependent healing was demonstrated. (C) 2007 Wiley Periodicals, Inc.
ISSN
1552-4973
URI
https://hdl.handle.net/10371/200269
DOI
https://doi.org/10.1002/jbm.b.31015
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Yun, Pil Young윤필영
(기금)부교수
  • School of Dentistry
  • Department of Dentistry
Research Area Dentistry, Oral Pathology, Oral and Maxillofacial Surgery, 구강병리학, 구강악안면외과학, 치의학

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