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Trans-differentiation via epigenetics: A new paradigm in the bone regeneration

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dc.contributor.authorCho, Young-Dan-
dc.contributor.authorRyoo, Hyun Mo-
dc.date.accessioned2024-05-02T06:03:03Z-
dc.date.available2024-05-02T06:03:03Z-
dc.date.created2019-09-19-
dc.date.created2019-09-19-
dc.date.created2019-09-19-
dc.date.issued2018-04-
dc.identifier.citation대한골대사학회지, Vol.25 No.1, pp.9-13-
dc.identifier.issn2287-6375-
dc.identifier.urihttps://hdl.handle.net/10371/200570-
dc.description.abstractIn regenerative medicine, growing cells or tissues in the laboratory is necessary when damaged cells can not heal by themselves. Acquisition of the required cells from the patients own cells or tissues is an ideal option without additive side effects. In this context, cell reprogramming methods, including the use of induced pluripotent stem cells (iPSCs) and trans-differentiation, have been widely studied in regenerative research. Both approaches have advantages and disadvantages, and the possibility of de-differentiation because of the epigenetic memory of iPSCs has strengthened the need for controlling the epigenetic background for successful cell reprogramming. Therefore, interest in epigenetics has increased in the field of regenerative medicine. Herein, we outline in detail the cell trans-differentiation method using epigenetic modification for bone regeneration in comparison to the use of iPSCs.-
dc.language영어-
dc.publisher대한골대사학회-
dc.titleTrans-differentiation via epigenetics: A new paradigm in the bone regeneration-
dc.typeArticle-
dc.identifier.doi10.11005/jbm.2018.25.1.9-
dc.citation.journaltitle대한골대사학회지-
dc.citation.endpage13-
dc.citation.number1-
dc.citation.startpage9-
dc.citation.volume25-
dc.identifier.kciidART002323039-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorCho, Young-Dan-
dc.contributor.affiliatedAuthorRyoo, Hyun Mo-
dc.type.docTypeArticle-
dc.description.journalClass2-
dc.subject.keywordAuthorBone regeneration, Cell transdifferentiation, Epigenomics, Induced pluripotentstem cells, Tissue engineering-
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Cho, Young-Dan조영단
(기금)조교수
  • School of Dentistry
  • Department of Dentistry
Research Area Alveolar bone regeneration, Dental implant surface modification, Periomics

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