Detailed Information

Predictors of the treatment response of spontaneous intracranial hypotension to an epidural blood patch

Cited 7 time in Web of Science Cited 7 time in Scopus

Karm, Myong Hwan; Choi, Jae Hyung; Kim, Doohwan; Park, Jun Young; Yun, Hye Joo; Suh, Jeong Hun

Issue Date
Lippincott Williams & Wilkins Ltd.
Medicine, Vol.95 No.18, p. e3578
Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.Spontaneous intracranial hypotension (SIH) is characterized by postural headache because of low cerebrospinal fluid (CSF) pressure. Brain magnetic resonance imaging (MRI) and radioisotope (RI) cisternography can be used to identify the site of a CSF leakage. Although autologous epidural blood patch (EBP) is a very effective treatment modality, some patients require a repeat autologous EBP. We investigated whether autologous EBP responses correlate with surrogate markers of quantitative findings. All cases of autologous EBP for SIH from January 2006 to December 2014 were enrolled. The demographic variables, number of EBPs, pain scores, RI cisternography (early visualization of bladder activity), and MRI findings (subdural fluid collections, pachymeningeal enhancement, engorgement of venous structures, pituitary hyperemia, and sagging of the brain) were reviewed. Patients with early bladder activity on RI cisternography had a tendency to need a higher number of autologous EBPs. Only sagging of the brain and no other variables showed a statistically significant negative correlation with the number of autologous EBPs. The response to autologous EBP may be related to the radiologic findings of early bladder activity on RI cisternography and sagging of the brain on MRI.
Files in This Item:
There are no files associated with this item.
Appears in Collections:

Related Researcher

Karm, Myong-Hwan Image

Karm, Myong-Hwan감명환
  • School of Dentistry
  • Department of Dentistry
Research Area Dental Anesthesiology, Pain Control, 치과마취, 치과진정법, 통증조절


Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.