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Osteogenic responses to zirconia with hydroxyapatite coating by aerosol deposition
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cho, Y. | - |
dc.contributor.author | Hong, J. | - |
dc.contributor.author | Ryoo, H. | - |
dc.contributor.author | Kim, D. | - |
dc.contributor.author | Park, J. | - |
dc.contributor.author | Han, J. | - |
dc.date.accessioned | 2024-05-02T06:06:53Z | - |
dc.date.available | 2024-05-02T06:06:53Z | - |
dc.date.created | 2018-10-04 | - |
dc.date.created | 2018-10-04 | - |
dc.date.created | 2018-10-04 | - |
dc.date.issued | 2015-03 | - |
dc.identifier.citation | Journal of Dental Research, Vol.94 No.3, pp.491-499 | - |
dc.identifier.issn | 0022-0345 | - |
dc.identifier.uri | https://hdl.handle.net/10371/200653 | - |
dc.description.abstract | Previously, we found that osteogenic responses to zirconia co-doped with niobium oxide (Nb2O5) or tantalum oxide (Ta2O5) are comparable with responses to titanium, which is widely used as a dental implant material. The present study aimed to evaluate the in vitro osteogenic potential of hydroxyapatite (HA)-coated zirconia by an aerosol deposition method for improved osseointegration. Surface analysis by scanning electron microscopy and x-ray diffraction proved that a thin as-deposited HA film on zirconia showed a shallow, regular, crater-like surface. Deposition of dense and uniform HA films was measured by SEM, and the contact angle test demonstrated improved wettability of the HA-coated surface. Confocal laser scanning microscopy indicated that MC3T3-E1 pre-osteoblast attachment did not differ notably between the titanium and zirconia surfaces; however, cells on the HA-coated zirconia exhibited a lower proliferation than those on the uncoated zirconia late in the culture. Nevertheless, ALP, alizarin red S staining, and bone marker gene expression analysis indicated good osteogenic responses on HA-coated zirconia. Our results suggest that HA-coating by aerosol deposition improves the quality of surface modification and is favorable to osteogenesis. | - |
dc.language | 영어 | - |
dc.publisher | SAGE Publications | - |
dc.title | Osteogenic responses to zirconia with hydroxyapatite coating by aerosol deposition | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/0022034514566432 | - |
dc.citation.journaltitle | Journal of Dental Research | - |
dc.identifier.wosid | 000350151400013 | - |
dc.identifier.scopusid | 2-s2.0-84924785738 | - |
dc.citation.endpage | 499 | - |
dc.citation.number | 3 | - |
dc.citation.startpage | 491 | - |
dc.citation.volume | 94 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Cho, Y. | - |
dc.contributor.affiliatedAuthor | Ryoo, H. | - |
dc.contributor.affiliatedAuthor | Han, J. | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | TITANIUM DENTAL IMPLANTS | - |
dc.subject.keywordPlus | ACID-ETCHED SURFACE | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | THICK-FILMS | - |
dc.subject.keywordPlus | BONE | - |
dc.subject.keywordPlus | OSSEOINTEGRATION | - |
dc.subject.keywordPlus | BIOCOMPATIBILITY | - |
dc.subject.keywordPlus | BIOMATERIAL | - |
dc.subject.keywordPlus | IMPROVEMENT | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordAuthor | implant dentistry | - |
dc.subject.keywordAuthor | biomaterial(s) | - |
dc.subject.keywordAuthor | osteogenesis | - |
dc.subject.keywordAuthor | surface chemistry | - |
dc.subject.keywordAuthor | osseointegration | - |
dc.subject.keywordAuthor | prosthetic dentistry | - |
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