Publications

Detailed Information

Comparison of the Osteogenic Potential of Titanium and Modified Zirconia-Based Bioceramics

Cited 16 time in Web of Science Cited 16 time in Scopus
Authors

Cho, Young-Dan; Shin, Ji-Cheol; Kim, Hye-Lee; Gerelmaa, Myagmar; Yoon, Hyung-In; Ryoo, Hyun-Mo; Kim, Dae-Joon; Han, Jung-Suk

Issue Date
2014-03
Publisher
Multidisciplinary Digital Publishing Institute (MDPI)
Citation
International Journal of Molecular Sciences, Vol.15 No.3, pp.4442-4452
Abstract
Zirconia is now favored over titanium for use in dental implant materials because of its superior aesthetic qualities. However, zirconia is susceptible to degradation at lower temperatures. In order to address this issue, we have developed modified zirconia implants that contain tantalum oxide or niobium oxide. Cells attached as efficiently to the zirconia implants as to titanium-based materials, irrespective of surface roughness. Cell proliferation on the polished surface was higher than that on the rough surfaces, but the converse was true for the osteogenic response. Cells on yttrium oxide (Y2O3)/tantalum oxide (Ta2O5)- and yttrium oxide (Y2O3)/niobium oxide (Nb2O5)-containing tetragonal zirconia polycrystals (TZP) discs ((Y, Ta)-TZP and (Y, Nb)-TZP, respectively) had a similar proliferative potential as those grown on anodized titanium. The osteogenic potential of MC3T3-E1 pre-osteoblast cells on (Y, Ta)-TZP and (Y, Nb)-TZP was similar to that of cells grown on rough-surface titanium. These data demonstrate that improved zirconia implants, which are resistant to temperature-induced degradation, retain the desirable clinical properties of structural stability and support of an osteogenic response.
ISSN
1661-6596
URI
https://hdl.handle.net/10371/200666
DOI
https://doi.org/10.3390/ijms15034442
Files in This Item:
There are no files associated with this item.
Appears in Collections:

Related Researcher

Cho, Young-Dan Image

Cho, Young-Dan조영단
(기금)조교수
  • School of Dentistry
  • Department of Dentistry
Research Area Alveolar bone regeneration, Dental implant surface modification, Periomics

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share