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Safety and efficacy of early high parenteral lipid supplementation in preterm infants: A systematic review and meta-analysis

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dc.contributor.authorKim, Kyunghoon-
dc.contributor.authorKim, Na Jin-
dc.contributor.authorKim, Sae Yun-
dc.date.accessioned2024-05-13T07:33:10Z-
dc.date.available2024-05-13T07:33:10Z-
dc.date.created2023-05-08-
dc.date.created2023-05-08-
dc.date.issued2021-05-
dc.identifier.citationNutrients, Vol.13 No.5, p. 1535-
dc.identifier.issn2072-6643-
dc.identifier.urihttps://hdl.handle.net/10371/201609-
dc.description.abstractThe objective of this systematic review and meta-analysis was to summarize the effects of early initiation and achievement of a high dose of parenteral lipids (>= 1.5 g/kg/day reached within the first 24 h of birth) on growth and adverse outcomes in preterm infants. PubMed, EMBASE, and Cochrane databases were utilized to search for publications for this meta-analysis. Randomized controlled trials were eligible if data on growth or clinical outcome was available. The search returned nine studies. The mean proportion of postnatal weight loss (%) was lower (mean difference [MD]: -2.73; 95% confidence interval [CI]: -3.69, -1.78), and the mean head circumference near the term equivalent age (cm) was higher in the early high lipid treatment group (MD: 0.67; 95% CI: 0.25, 1.09). There was a favorable association of early high lipid administration with the incidence of extrauterine growth restriction (relative risk [RR]: 0.27; 95% CI: 0.15, 0.48). Generally, there were no differences in morbidities or adverse outcomes with early high lipid administration. Early initiation of parenteral lipids and high dose achieved within the first 24 h of life appear to be safe and endurable and offer benefits in terms of growth.-
dc.language영어-
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)-
dc.titleSafety and efficacy of early high parenteral lipid supplementation in preterm infants: A systematic review and meta-analysis-
dc.typeArticle-
dc.identifier.doi10.3390/nu13051535-
dc.citation.journaltitleNutrients-
dc.identifier.wosid000662454700001-
dc.identifier.scopusid2-s2.0-85107446862-
dc.citation.number5-
dc.citation.startpage1535-
dc.citation.volume13-
dc.description.isOpenAccessY-
dc.contributor.affiliatedAuthorKim, Kyunghoon-
dc.type.docTypeReview-
dc.description.journalClass1-
dc.subject.keywordPlusRANDOMIZED CONTROLLED-TRIAL-
dc.subject.keywordPlusCHRONIC LUNG-DISEASE-
dc.subject.keywordPlusBIRTH-
dc.subject.keywordPlusNUTRITION-
dc.subject.keywordPlusGROWTH-
dc.subject.keywordPlusEMULSIONS-
dc.subject.keywordAuthorAdverse effect-
dc.subject.keywordAuthorGrowth-
dc.subject.keywordAuthorLipids-
dc.subject.keywordAuthorPreterm infants-
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  • College of Medicine
  • Department of Medicine
Research Area 식품알레르기, 아토피피부염, 천식

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