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Determining the value of TB active case-finding: current evidence and methodological considerations

Cited 11 time in Web of Science Cited 12 time in Scopus
Authors

Sohn, H.; Sweeney, S.; Mudzengi, D.; Creswell, J.; Menzies, N. A.; Fox, G. J.; MacPherson, P.; Dowdy, D. W.

Issue Date
2021-03
Publisher
INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D)
Citation
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Vol.25 No.3, pp.171-+
Abstract
Active case-finding (ACF) is an important component of the End TB Strategy. However, ACF is resource intensive, and the economics of ACF are not well understood. Data on the costs of ACF are limited, with little consistency in the units and methods used to estimate and report costs. Mathematical models to forecast the long-term effects of ACF require empirical measurements of the yield, timing and costs of case detection. Pragmatic trials offer an opportunity to assess the cost-effectiveness of ACF interventions within a 'real-world' context. However, such analyses generally require early introduction of economic evaluations to enable prospective data collection on resource requirements. Closing the global case-detection gap will require substantial additional resources, including continued investment in innovative technologies. Research is essential to the optimal implementation, cost-effectiveness, and affordability of ACF in high-burden settings. To assess the value of ACF, we must prioritize the collection of high-quality data regarding costs and effectiveness, and link those data to analytical models that are adapted to local settings.
ISSN
1027-3719
URI
https://hdl.handle.net/10371/201749
DOI
https://doi.org/10.5588/ijtld.20.0565
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  • College of Medicine
  • Department of Human Systems Medicine
Research Area 결핵, 국제보건, 에이즈

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