Publications
Detailed Information
Multicentre evaluation of Ziehl-Neelsen and light-emitting diode fluorescence microscopy in China
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Xia, H. | - |
dc.contributor.author | Song, Y-Y. | - |
dc.contributor.author | Zhao, B. | - |
dc.contributor.author | Kam, K-M. | - |
dc.contributor.author | O'Brien, R. J. | - |
dc.contributor.author | Zhang, Z-Y. | - |
dc.contributor.author | Sohn, H. | - |
dc.contributor.author | Wang, W. | - |
dc.contributor.author | Zhao, Y-L. | - |
dc.date.accessioned | 2024-05-14T04:35:40Z | - |
dc.date.available | 2024-05-14T04:35:40Z | - |
dc.date.created | 2024-05-14 | - |
dc.date.issued | 2013-01 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Vol.17 No.1, pp.107-112 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | https://hdl.handle.net/10371/201771 | - |
dc.description.abstract | OBJECTIVE: To assess the feasibility of using light-emitting diode fluorescence microscopy (LED-FM) in peripheral laboratories in China. DESIGN: The performance of LED-FM and Ziehl-Neelsen (ZN) microscopy was compared on slides directly prepared from the sputum of tuberculosis (TB) suspects and follow-up patients on treatment. The examination time, fading of fluorescence-stained slides, average unit cost and qualitative user appraisal of LED-FM were also analysed. RESULTS: Among 11 276 slides, the smear-positive rate for LED-FM was 11.2% (1263/11276), 2.6% (294/11 276) higher than that of ZN (8.6%, 969/11276; chi(2)263.5, P < 0.05). The examination time for LED-FM (120.0 +/- 38.9 seconds) was shorter than that for ZN (206.3 +/- 75.9 s; t = 28.12, P < 0.05). For smear fading, quantitative and qualitative errors occurred within respectively 7.8 and 7.7 weeks. The average unit costs for ZN and LED-FM were respectively US$2.20 +/- 0.58 and US$1.97 +/- 0.71 (t = 5.08, P < 0.05). LED-FM was accepted by most laboratory technicians. CONCLUSION: LED-FM compared favourably with ZN, with a higher smear-positive detection rate, a shorter examination time and lower unit examination cost. LED-FM may be an alternative to ZN as a cost-effective method for detecting bacilli in peripheral laboratories in China. | - |
dc.language | 영어 | - |
dc.publisher | INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D) | - |
dc.title | Multicentre evaluation of Ziehl-Neelsen and light-emitting diode fluorescence microscopy in China | - |
dc.type | Article | - |
dc.identifier.doi | 10.5588/ijtld.12.0184 | - |
dc.citation.journaltitle | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
dc.identifier.wosid | 000313227600020 | - |
dc.identifier.scopusid | 2-s2.0-84871236730 | - |
dc.citation.endpage | 112 | - |
dc.citation.number | 1 | - |
dc.citation.startpage | 107 | - |
dc.citation.volume | 17 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Sohn, H. | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordAuthor | pulmonary tuberculosis | - |
dc.subject.keywordAuthor | smear microscopy | - |
dc.subject.keywordAuthor | light-emitting diode fluorescence microscopy | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.