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C-terminal de novo sequencing of peptides using oxazolone-based derivatization with bromine signature
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jong-Seo | - |
dc.contributor.author | Shin, Mansup | - |
dc.contributor.author | Song, Jin-Su | - |
dc.contributor.author | An, Songhie | - |
dc.contributor.author | Kim, Hie-Joon | - |
dc.date.accessioned | 2024-05-14T06:49:25Z | - |
dc.date.available | 2024-05-14T06:49:25Z | - |
dc.date.created | 2021-11-03 | - |
dc.date.issued | 2011-12 | - |
dc.identifier.citation | Analytical Biochemistry, Vol.419 No.2, pp.211-216 | - |
dc.identifier.issn | 0003-2697 | - |
dc.identifier.uri | https://hdl.handle.net/10371/201903 | - |
dc.description.abstract | Due to almost identical chemical properties of C-terminal and side-chain carboxylic groups, selective C-terminal derivatization has been difficult. Although oxazolone-based C-terminal derivatization is the only selective C-terminal modification available, it has not been used widely because of its low derivatization efficiency. In this paper, an improved oxazolone chemistry for incorporation of Br signature to C-terminus is reported. MS/MS analysis of the brominated peptides led to a series of y ions with Br signature, facilitating de novo C-terminal sequencing. (C) 2011 Elsevier Inc. All rights reserved. | - |
dc.language | 영어 | - |
dc.publisher | Academic Press | - |
dc.title | C-terminal de novo sequencing of peptides using oxazolone-based derivatization with bromine signature | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.ab.2011.08.011 | - |
dc.citation.journaltitle | Analytical Biochemistry | - |
dc.identifier.wosid | 000296119400021 | - |
dc.identifier.scopusid | 2-s2.0-80054063140 | - |
dc.citation.endpage | 216 | - |
dc.citation.number | 2 | - |
dc.citation.startpage | 211 | - |
dc.citation.volume | 419 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Kim, Jong-Seo | - |
dc.contributor.affiliatedAuthor | Kim, Hie-Joon | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | DESORPTION/IONIZATION MASS-SPECTROMETRY | - |
dc.subject.keywordPlus | PROTEIN N-TERMINI | - |
dc.subject.keywordPlus | ACETIC-ANHYDRIDE | - |
dc.subject.keywordPlus | CYANOGEN-BROMIDE | - |
dc.subject.keywordPlus | CLEAVAGE SITES | - |
dc.subject.keywordPlus | PROTEOMIC ERA | - |
dc.subject.keywordPlus | SULFONATION | - |
dc.subject.keywordPlus | FRAGMENTS | - |
dc.subject.keywordPlus | ACID | - |
dc.subject.keywordPlus | PHOSPHORYLATION | - |
dc.subject.keywordAuthor | Br signature | - |
dc.subject.keywordAuthor | De novo sequencing | - |
dc.subject.keywordAuthor | C-terminal | - |
dc.subject.keywordAuthor | Derivatization | - |
dc.subject.keywordAuthor | Oxazolone | - |
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