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One-Pot Synthesis of 4-Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Arene
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Seok Beom | - |
dc.contributor.author | Jang, Yoonkyung | - |
dc.contributor.author | Ahn, Jiwon | - |
dc.contributor.author | Chun, Simin | - |
dc.contributor.author | Oh, Dong-Chan | - |
dc.contributor.author | Hong, Suckchang | - |
dc.date.accessioned | 2024-05-14T07:16:59Z | - |
dc.date.available | 2024-05-14T07:16:59Z | - |
dc.date.created | 2021-02-01 | - |
dc.date.issued | 2020-11-06 | - |
dc.identifier.citation | Organic Letters, Vol.22 No.21, pp.8382-8386 | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.uri | https://hdl.handle.net/10371/202003 | - |
dc.description.abstract | Herein, we describe the iron(III)-catalyzed oxidative coupling of alcohol/methyl arene with 2-amino phenyl ketone to synthesize 4-quinolone. Alcohols and methyl arenes are oxidized to the aldehyde in the presence of an iron catalyst and di-tert-butyl peroxide, followed by a tandem process, condensation with amine/Mannich-type cyclization/oxidation, to complete the 4-quinolone ring. This method tolerates various kinds of functional groups and provides a direct approach to the synthesis of 4-quinolones from less functionalized substrates. | - |
dc.language | 영어 | - |
dc.publisher | American Chemical Society | - |
dc.title | One-Pot Synthesis of 4-Quinolone via Iron-Catalyzed Oxidative Coupling of Alcohol and Methyl Arene | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/acs.orglett.0c03011 | - |
dc.citation.journaltitle | Organic Letters | - |
dc.identifier.wosid | 000589942900038 | - |
dc.identifier.scopusid | 2-s2.0-85095861249 | - |
dc.citation.endpage | 8386 | - |
dc.citation.number | 21 | - |
dc.citation.startpage | 8382 | - |
dc.citation.volume | 22 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Oh, Dong-Chan | - |
dc.contributor.affiliatedAuthor | Hong, Suckchang | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | ANTITUMOR AGENTS | - |
dc.subject.keywordPlus | 2-ARYL-4-QUINOLONES | - |
dc.subject.keywordPlus | CYCLIZATION | - |
dc.subject.keywordPlus | INHIBITORS | - |
dc.subject.keywordPlus | AMIDATION | - |
dc.subject.keywordPlus | SCAFFOLD | - |
dc.subject.keywordPlus | ARYL | - |
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