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Formicins, N-Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Du, Young Eun | - |
| dc.contributor.author | Byun, Woong Sub | - |
| dc.contributor.author | Lee, Seok Beom | - |
| dc.contributor.author | Hwang, Sunghoon | - |
| dc.contributor.author | Shin, Yern-Hyerk | - |
| dc.contributor.author | Shin, Bora | - |
| dc.contributor.author | Jang, Yong-Joon | - |
| dc.contributor.author | Hong, Suckchang | - |
| dc.contributor.author | Shin, Jongheon | - |
| dc.contributor.author | Lee, Sang Kook | - |
| dc.contributor.author | Oh, Dong-Chan | - |
| dc.date.accessioned | 2024-05-14T07:17:12Z | - |
| dc.date.available | 2024-05-14T07:17:12Z | - |
| dc.date.created | 2020-08-10 | - |
| dc.date.issued | 2020-07 | - |
| dc.identifier.citation | Organic Letters, Vol.22 No.14, pp.5337-5341 | - |
| dc.identifier.issn | 1523-7060 | - |
| dc.identifier.uri | https://hdl.handle.net/10371/202006 | - |
| dc.description.abstract | Formicins A - C (1-3) were discovered from Streptomyces sp. associated with wood ants. The structures of 1 and 2 were elucidated as indenone thioesters bearing N-acetylcysteamine based on spectroscopic analysis. The configurations of 1-3 were determined by the analysis of ROESY correlations, the phenylglycine methyl ester method, and chemical derivatization from 3 to 2. Formicin A inhibited the growth of human triple-negative breast cancer cells by regulating the liver kinase B1-mediated AMPK signaling pathway. | - |
| dc.language | 영어 | - |
| dc.publisher | American Chemical Society | - |
| dc.title | Formicins, N-Acetylcysteamine-Bearing Indenone Thioesters from a Wood Ant-Associated Bacterium | - |
| dc.type | Article | - |
| dc.identifier.doi | 10.1021/acs.orglett.0c01584 | - |
| dc.citation.journaltitle | Organic Letters | - |
| dc.identifier.wosid | 000551552600013 | - |
| dc.identifier.scopusid | 2-s2.0-85088139995 | - |
| dc.citation.endpage | 5341 | - |
| dc.citation.number | 14 | - |
| dc.citation.startpage | 5337 | - |
| dc.citation.volume | 22 | - |
| dc.description.isOpenAccess | N | - |
| dc.contributor.affiliatedAuthor | Hong, Suckchang | - |
| dc.contributor.affiliatedAuthor | Shin, Jongheon | - |
| dc.contributor.affiliatedAuthor | Lee, Sang Kook | - |
| dc.contributor.affiliatedAuthor | Oh, Dong-Chan | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.subject.keywordPlus | LKB1 | - |
| dc.subject.keywordPlus | CANCER | - |
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