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Efficient synthetic method of Psammaplin A

Cited 9 time in Web of Science Cited 9 time in Scopus
Authors

Hong, Suckchang; Lee, Myungmo; Jung, Myunggi; Park, Yohan; Kim, Mi-hyun; Park, Hyeung-geun

Issue Date
2012-08
Publisher
Elsevier BV
Citation
Tetrahedron Letters, Vol.53 No.32, pp.4209-4211
Abstract
A new concise and efficient synthetic method of Psammaplin A was developed. Psammaplin A was obtained with 50% overall yield in nine steps from p-hydroxybenzaldehyde and ethyl acetoacetate via Knoevenagel condensation and direct nitrosation as key steps. This method might be very efficient to construct a quite diverse library of Psammaplin A type analogs. (C) 2012 Elsevier Ltd. All rights reserved.
ISSN
0040-4039
URI
https://hdl.handle.net/10371/202030
DOI
https://doi.org/10.1016/j.tetlet.2012.05.149
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Related Researcher

  • College of Pharmacy
  • Department of Manufacturing Pharmacy
Research Area Development of methodologies using metal catalyst, Total synthesis of natural products

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