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Highly enantioselective total synthesis of (+)-isonitramine

DC Field Value Language
dc.contributor.authorPark, Yohan-
dc.contributor.authorLee, Young Ju-
dc.contributor.authorHong, Suck Chang-
dc.contributor.authorLee, Myungmo-
dc.contributor.authorPark, Hyeung-geun-
dc.date.accessioned2024-05-14T07:18:58Z-
dc.date.available2024-05-14T07:18:58Z-
dc.date.created2017-11-15-
dc.date.issued2012-02-
dc.identifier.citationOrganic Letters, Vol.14 No.3, pp.852-854-
dc.identifier.issn1523-7060-
dc.identifier.urihttps://hdl.handle.net/10371/202032-
dc.description.abstractA new efficient enantioselective synthetic method of (+)-isonitramine is reported. (+)-Isonitramine was obtained in 12 steps (98% ee and 43% overall yield) from delta-valerolactam via enantioselective phase-transfer catalytic alkylation, Dieckman condensation, and diastereoselective reduction as key steps.-
dc.language영어-
dc.publisherAmerican Chemical Society-
dc.titleHighly enantioselective total synthesis of (+)-isonitramine-
dc.typeArticle-
dc.identifier.doi10.1021/ol2033042-
dc.citation.journaltitleOrganic Letters-
dc.identifier.wosid000300458200047-
dc.identifier.scopusid2-s2.0-84863022512-
dc.citation.endpage854-
dc.citation.number3-
dc.citation.startpage852-
dc.citation.volume14-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorHong, Suck Chang-
dc.contributor.affiliatedAuthorPark, Hyeung-geun-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.subject.keywordPlusPHASE-TRANSFER CATALYSIS-
dc.subject.keywordPlusNITRARIA ALKALOIDS-
dc.subject.keywordPlusASYMMETRIC ALKYLATION-
dc.subject.keywordPlusBETA-KETOESTERS-
dc.subject.keywordPlus(-)-SIBIRINE-
dc.subject.keywordPlus(+)-NITRAMINE-
dc.subject.keywordPlus(-)-NITRAMINE-
dc.subject.keywordPlusCONSTRUCTION-
dc.subject.keywordPlusCYCLIZATION-
dc.subject.keywordPlusESTERS-
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  • College of Pharmacy
  • Department of Manufacturing Pharmacy
Research Area Development of methodologies using metal catalyst, Total synthesis of natural products

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