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Fabrication of 2D and 3D Cell Cluster Arrays Using a Cell-Friendly Photoresist

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dc.contributor.authorPark, Jeehun-
dc.contributor.authorKim, Seong-Eun-
dc.contributor.authorCho, Yongbum-
dc.contributor.authorAn, Seongmin-
dc.contributor.authorMoon, Dowon-
dc.contributor.authorPark, Inae-
dc.contributor.authorDoh, Junsang-
dc.date.accessioned2024-05-16T01:21:34Z-
dc.date.available2024-05-16T01:21:34Z-
dc.date.created2021-07-30-
dc.date.created2021-07-30-
dc.date.issued2021-07-12-
dc.identifier.citationACS Biomaterial Science and Engineering, Vol.7 No.7, pp.3082-3087-
dc.identifier.issn2373-9878-
dc.identifier.urihttps://hdl.handle.net/10371/202457-
dc.description.abstractCells in 3D behave differently than cells in 2D. We develop a new method for the fabrication of 2D and 3D cell cluster arrays on an identical substrate using a cell-friendly photoresist, which enables comparative study between cells in 2D and 3D cell clusters. The fabricated cell cluster arrays maintain their structure up to 3 days with good viability. Using this method, 2D and 3D cancer cell clusters with comparable sizes are fabricated, and natural killer (NK) cell cytotoxicity assays are performed to assess how dimensionality of cancer cell clusters influence their susceptibility to immune cell-mediated killing.-
dc.language영어-
dc.publisherAmerican Chemical Society-
dc.titleFabrication of 2D and 3D Cell Cluster Arrays Using a Cell-Friendly Photoresist-
dc.typeArticle-
dc.identifier.doi10.1021/acsbiomaterials.1c00655-
dc.citation.journaltitleACS Biomaterial Science and Engineering-
dc.identifier.wosid000674162000018-
dc.identifier.scopusid2-s2.0-85108990872-
dc.citation.endpage3087-
dc.citation.number7-
dc.citation.startpage3082-
dc.citation.volume7-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorDoh, Junsang-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.subject.keywordPlusCULTURE-
dc.subject.keywordPlusSPHEROIDS-
dc.subject.keywordAuthorCell clusters-
dc.subject.keywordAuthorcell-friendly photoresist-
dc.subject.keywordAuthormicropatterning-
dc.subject.keywordAuthorNK cell-
dc.subject.keywordAuthorcytotoxicity-
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  • College of Engineering
  • Department of Materials Science & Engineering
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