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Fast and sensitive taxonomic assignment to metagenomic contigs

Cited 75 time in Web of Science Cited 78 time in Scopus
Authors

Mirdita, M.; Steinegger, Martin; Breitwieser, F.; Soeding, J.; Karin, E. Levy

Issue Date
2021-09
Publisher
Oxford University Press
Citation
Bioinformatics, Vol.37 No.18, pp.3029-3031
Abstract
A Summary: MMseqs2 taxonomy is a new tool to assign taxonomic labels to metagenomic contigs. It extracts all possible protein fragments from each contig, quickly retains those that can contribute to taxonomic annotation, assigns them with robust labels and determines the contig's taxonomic identity by weighted voting. Its fragment extraction step is suitable for the analysis of all domains of life. MMseqs2 taxonomy is 2-18x faster than state-of-the-art tools and also contains new modules for creating and manipulating taxonomic reference databases as well as reporting and visualizing taxonomic assignments.
ISSN
1367-4803
URI
https://hdl.handle.net/10371/202552
DOI
https://doi.org/10.1093/bioinformatics/btab184
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  • College of Natural Sciences
  • School of Biological Sciences
Research Area Development of algorithms to search, cluster and assemble sequence data, Metagenomic analysis, Pathogen detection in sequencing data

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