Publications

Detailed Information

Biomechanical Effects of Fluid Dynamics and Mass Transport on Cell Growth in Perfusion Bioreactors for Tissue Engineering

DC Field Value Language
dc.contributor.authorLim, Ki-Taek-
dc.contributor.authorSeonwoo, Hoon-
dc.contributor.authorSon, Hyun-Mok-
dc.contributor.authorBaik, Soo-Jung-
dc.contributor.authorKim, Jang-Ho-
dc.contributor.authorJeon, Soung-Hoo-
dc.contributor.authorPark, Joo-Young-
dc.contributor.authorChoung, Yun-Hoon-
dc.contributor.authorCho, Chong-Su-
dc.contributor.authorChoung, Pill-Hoon-
dc.contributor.authorChung, Jong Hoon-
dc.date.accessioned2024-05-16T01:40:17Z-
dc.date.available2024-05-16T01:40:17Z-
dc.date.created2018-01-19-
dc.date.created2018-01-19-
dc.date.created2018-01-19-
dc.date.issued2009-12-
dc.identifier.citation조직공학과 재생의학, Vol.6 No.14, pp.1327-1342-
dc.identifier.issn1738-2696-
dc.identifier.urihttps://hdl.handle.net/10371/202773-
dc.description.abstractIn the design of perfusion bioreactor system for tissue engineering, design parameters including fluid dynamics and mass transport as well as scaffolds Should be optimized to maximize cell growth. Critical elements in bioreactor systems based oil cells and scaffolds include cell seeding, the nutrient and gas Supply to Cells, and mechanical stimuli. In particular, perfusion flow systems have been shown to enhance cell growth, differentiation, and tissue formation as well as provide for the appropriate and necessary mass transfer of nutrients, gases, metabolites, and regulatory molecules. In this paper, we reviewed the biomechanical models in relation with fluid dynamics, mass transport, and shear stress with scaffolds. Therefore, obtaining a proper oxygen supply, high cell density, and all uniform cell distribution in a three-dimensional growth Support are important. Both experiments and quantitative mathematical models of cell Culture in perfusion bioreactors are needed to better understand physical, mechanical, and biochemical conditions and for the design of a Suitable bioreactor system the mathematical describes the oxygen mass transfer and cell density within a three-dimensional scaffold. This review focuses on biomechanical models in relation with fluid dynamics, mass transport, and shear stress to cells cultured, and cell growth in perfusion bioreactors for tissue engineering.-
dc.language영어-
dc.publisher한국조직공학과 재생의학회-
dc.titleBiomechanical Effects of Fluid Dynamics and Mass Transport on Cell Growth in Perfusion Bioreactors for Tissue Engineering-
dc.typeArticle-
dc.citation.journaltitle조직공학과 재생의학-
dc.identifier.wosid000273647500001-
dc.identifier.scopusid2-s2.0-84884549757-
dc.citation.endpage1342-
dc.citation.number14-
dc.citation.startpage1327-
dc.citation.volume6-
dc.identifier.kciidART001414842-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorPark, Joo-Young-
dc.contributor.affiliatedAuthorCho, Chong-Su-
dc.contributor.affiliatedAuthorChoung, Pill-Hoon-
dc.contributor.affiliatedAuthorChung, Jong Hoon-
dc.type.docTypeReview-
dc.description.journalClass1-
dc.subject.keywordPlusMARROW STROMAL CELLS-
dc.subject.keywordPlusMINERALIZED MATRIX DEPOSITION-
dc.subject.keywordPlusIN-VITRO-
dc.subject.keywordPlusFLOW PERFUSION-
dc.subject.keywordPlusFINITE-ELEMENT-
dc.subject.keywordPlusOSTEOGENIC DIFFERENTIATION-
dc.subject.keywordPlusOSTEOBLASTIC CELLS-
dc.subject.keywordPlusMECHANICAL STIMULI-
dc.subject.keywordPlusLOW-MAGNITUDE-
dc.subject.keywordPlusSHEAR-STRESS-
dc.subject.keywordAuthorFluid dynamics-
dc.subject.keywordAuthorMass transport-
dc.subject.keywordAuthorPerfusion bioreactors-
dc.subject.keywordAuthorBiomechanical models-
Appears in Collections:
Files in This Item:
There are no files associated with this item.

Related Researcher

  • School of Dentistry
  • Department of Dentistry
Research Area 구강 및 턱뼈 (구강악안면) 의 면역 항상성 유지기전에 대한 연구

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share