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Design of artificial metalloenzymes with multiple inorganic elements: The more the merrier
DC Field | Value | Language |
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dc.contributor.author | Jung, Se-Min | - |
dc.contributor.author | Lee, Jaehee | - |
dc.contributor.author | Song, Woon Ju | - |
dc.date.accessioned | 2024-05-16T01:51:00Z | - |
dc.date.available | 2024-05-16T01:51:00Z | - |
dc.date.created | 2021-09-13 | - |
dc.date.issued | 2021-10 | - |
dc.identifier.citation | Journal of Inorganic Biochemistry, Vol.223, p. 111552 | - |
dc.identifier.issn | 0162-0134 | - |
dc.identifier.uri | https://hdl.handle.net/10371/202915 | - |
dc.description.abstract | A large fraction of metalloenzymes harbors multiple metal-centers that are electronically and/or functionally arranged within their proteinaceous environments. To explore the orchestration of inorganic and biochemical components and to develop bioinorganic catalysts and materials, we have described selected examples of artificial metalloproteins having multiple metallocofactors that were grouped depending on their initial protein scaffolds, the nature of introduced inorganic moieties, and the method used to propagate the number of metal ions within a protein. They demonstrated that diverse inorganic moieties can be selectively grafted and modulated in protein environments, providing a retrosynthetic bottom-up approach in the design of versatile and proficient biocatalysts and biomimetic model systems to explore fundamental questions in bioinorganic chemistry. | - |
dc.language | 영어 | - |
dc.publisher | Elsevier BV | - |
dc.title | Design of artificial metalloenzymes with multiple inorganic elements: The more the merrier | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.jinorgbio.2021.111552 | - |
dc.citation.journaltitle | Journal of Inorganic Biochemistry | - |
dc.identifier.wosid | 000691182000001 | - |
dc.identifier.scopusid | 2-s2.0-85111310550 | - |
dc.citation.startpage | 111552 | - |
dc.citation.volume | 223 | - |
dc.description.isOpenAccess | N | - |
dc.contributor.affiliatedAuthor | Song, Woon Ju | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.subject.keywordPlus | DE-NOVO DESIGN | - |
dc.subject.keywordPlus | CARBONIC-ANHYDRASE | - |
dc.subject.keywordPlus | HYDROGEN EVOLUTION | - |
dc.subject.keywordPlus | CRYSTAL-STRUCTURE | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | COPPER | - |
dc.subject.keywordPlus | IRON | - |
dc.subject.keywordPlus | METALLOPROTEINS | - |
dc.subject.keywordPlus | COMPLEXES | - |
dc.subject.keywordPlus | REDUCTION | - |
dc.subject.keywordAuthor | Artificial metalloenzyme | - |
dc.subject.keywordAuthor | Multiple metallocofactor | - |
dc.subject.keywordAuthor | Metalloprotein design | - |
dc.subject.keywordAuthor | Biomimetic protein | - |
dc.subject.keywordAuthor | Multinuclear metalloprotein | - |
dc.subject.keywordAuthor | Biocatalysts | - |
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