Publications

Detailed Information

Immunological Synapses Within Context: Patterns of Cell-Cell Communication and Their Application in T-T Interactions

DC Field Value Language
dc.contributor.authorDoh, Junsang-
dc.contributor.authorKrummel, Matthew F.-
dc.date.accessioned2024-05-17T07:41:10Z-
dc.date.available2024-05-17T07:41:10Z-
dc.date.created2024-05-17-
dc.date.issued2010-
dc.identifier.citationCurrent Topics in Microbiology and Immunology, Vol.340, pp.25-50-
dc.identifier.issn0070-217X-
dc.identifier.urihttps://hdl.handle.net/10371/203233-
dc.description.abstractThe cell-biology of intercellular communication between T cells and their partners has been greatly advanced over the past 10 years. The key morphological and motility features of cell contact-based communication between T cells and APCs can now be seen as a collection of patterns for cell-cell interactions amongst immune cells more generally, each serving to contribute to the outcome of the contact both locally and globally. Here we review the conservation of these patterns, amongst which is the emergent "immunological synapse," and describe a newly defined example, formed between the adjacent activating T cells. We subsequently seek to put these and the pattern more generally into the framework of system-wide behavior of the immune system. We postulate that the patterns are fine-tuned to provide quorum-like decisions by collections of activating and activated cells that interact over time and space.-
dc.language영어-
dc.publisherSpringer Verlag-
dc.titleImmunological Synapses Within Context: Patterns of Cell-Cell Communication and Their Application in T-T Interactions-
dc.typeArticle-
dc.identifier.doi10.1007/978-3-642-03858-7_2-
dc.citation.journaltitleCurrent Topics in Microbiology and Immunology-
dc.identifier.wosid000274501800002-
dc.identifier.scopusid2-s2.0-77950901884-
dc.citation.endpage50-
dc.citation.startpage25-
dc.citation.volume340-
dc.description.isOpenAccessN-
dc.contributor.affiliatedAuthorDoh, Junsang-
dc.type.docTypeReview; Book Chapter-
dc.description.journalClass1-
dc.subject.keywordPlusRECEPTOR ALPHA-CHAIN-
dc.subject.keywordPlusSPLENIC B-CELLS-
dc.subject.keywordPlusDENDRITIC CELLS-
dc.subject.keywordPlusLYMPH-NODES-
dc.subject.keywordPlusIN-VIVO-
dc.subject.keywordPlusANTIGEN PRESENTATION-
dc.subject.keywordPlusCUTTING EDGE-
dc.subject.keywordPlusDYNAMIC INTERACTIONS-
dc.subject.keywordPlusCYTOKINE-RECEPTOR-
dc.subject.keywordPlusCRYSTAL-STRUCTURE-
Appears in Collections:
Files in This Item:
There are no files associated with this item.

Related Researcher

  • College of Engineering
  • Department of Materials Science & Engineering
Research Area Ex Vivo Models, Lymphocyte Biology, Smart Biomaterials

Altmetrics

Item View & Download Count

  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Share